Carotid compression in patients with transient ischemic attacks.
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Carotid Arteries↗
Biomedical subjects
G Meneghetti
Publications and source records attributed to G Meneghetti.
Long-term treatment of Parkinson's disease with L-Dopa and Dopa-decarboxylase inhibitor: therapeutic results and side effects.
The authors present a review of their clinical experience in the treatment of 127 Parkinsonian patients with L-Dopa alone and in association with a Dopa-decarboxylase inhibitor; the follow-up lasted more than 7 years. In all cases the dosages of L-Dopa, either alone or associated with the decarboxylase inhibitor, were fairly low; the strategy was to reach in each case the minimal effective dose instead of the maximal tolerable one. After 7 years of treatment about 60-65% of the patients had shown improvement, even though to a lesser degree than during the first and second year of therapy; the remaining 35-40% were unchanged or worse. The authors conclude that, despite the decreased efficacy of the therapy with time, the L-Dopa treatment remains of great significance in lengthening and in improving the quality of life of Parkinsonian patients.
Aromatic Amino Acid Decarboxylase Inhibitors↗
[Carotid stenosis and obliteration of the contralateral carotid. A prospective study of the risks of a carotid endarterectomy intervention and its long-term results].
From March 1980 to July 1988 a consecutive series of 256 patients (p.) underwent 301 carotid endarterectomy + patch with routine use of continuous intraoperative EEG monitoring and selective use of an intraluminal shunt (IS) for the presence of an atherosclerotic plaque concerning the internal carotid artery (ICA). Patients were divided in two groups: the first (42 p.) marked by contralateral ICA occlusion, the second (214 p.) without contralateral ICA occlusion (259 CEA). Immediate peroperative, long term and global (immediate and long term) outcomes were prospectively and comparatively studied. A temporary IS was inserted in 27 p. (64%) of the group I and in 38 p. (14%) of the group II. Immediate permanent postoperative neurological deficit occurred in 1 p. of group I (2.38%) and in 2 p. (0.9%) in group II. Immediate postoperative mortality was 0% and 0.9% in group I and II respectively. All p. had neurological valuation and Echo-Doppler of operated ICA and of the contralateral ICA every 6 months (middle follow-up 44 months). New neurological symptoms compared in 5.8% of p. of group I and in 5.23% of p. of group II with a stroke rate of 0% and 2.32% respectively. There were 2 restenosis of operated ICA, both of them in p. of group I, that underwent reoperation. In the two groups the principal causes of deaths were myocardial infarct and cancer; in the group I no death was due to stroke versus 1.86% in the group II.
Aged↗
Hyperbaric oxygen therapy in the treatment of multiple sclerosis. A clinical and electrophysiological study in a 2 year follow-up.
15 patients with chronic progressive Multiple Sclerosis were treated with Hyperbaric Oxygen Therapy at 2.0 atmospheres absolute for a total of 20 daily exposures followed by 2 exposures every month. The treatment was carried out for a 24 months follow-up. No objective benefit resulted from Hyperbaric Oxygen Therapy at the completion of the study while a subjective improvement in bladder control was reported in the short and in the long-term follow-up by 8 and by 5 patients respectively. No significant variations in the electrophysiological results were observed after the first 20 consecutive exposures. It is concluded from this trial that a long-term Hyperbaric Oxygen Treatment cannot moderate the progression of Multiple Sclerosis. However, an improvement in the quality of life can be obtained in some patients resulting from a better control of bladder function.
Adult↗
[Type I Arnold-Chiari malformation: diagnostic considerations in a case].
An 18-year-old patient with a 5-year history of periodic vertigo, headache and stiff neck is reported. Routine X-ray of the skull showed a mild form of basilar impression while the CT scan demonstrated only a tri-ventricular hydrocephalus. Without using the traditional invasive techniques, diagnosis of Chiari type I malformation was nonetheless clearly pointed out by magnetic resonance imaging of the posterior fossa and spinal cord. Diagnostic problems of this clinically ambiguous and uncharacterized syndrome are discussed.
Adolescent↗
Electroencephalographic and histopathological correlations on Jakob-Creutzfeldt disease.
Three patients with Jakob-Creutzfeldt disease were studied. The clinical evolution was followed and several EEG controls were made. In all patients characteristic EEG abnormalities were present. Histopathological features in the cortical, subcortical grey matter and in the white matter were examined. Subcortical and cortical grey matter were involved while the white matter appeared intact. The results were compared with previous studies of other Authors and the correlation between the characteristic EEG alterations and the histopathological features was studied in order to explain the appearance of the paroxysmal EEG findings. In agreement with other studies, the Authors emphasized the cortical and subcortical grey matter involvement in the genesis of EEGraphic paroxysmal aspects. The intervention of other factors, possibly of histochemical nature, was postulated.
Aged↗
Clinical-electroencephalographic correlations in measles: a long range study of 18 subjects.
EEGs of 18 cases of measles (uncomplicated, with seizures, with encephalitides) were obtained through an underground cable connection between the Infections Diseases Department and the EEG unit. The varions EEG features of the disease have been studied during the evolution of the illness. An occasional EEG does not offer specific information on either the severity or the evolution of the disease. Marked EEG abnormalities appeared in the encephalitic group. The Authors emphasize the importance of serial prolonged EEG follow-up of measles in order to define precisely the stage and the evolution of the disease.
Adolescent↗