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Biomedical subjects

G Methfessel

Publications and source records attributed to G Methfessel.

15 recordsLinked to original sources
PubMed1992

[Urinary fistula after radical hysterectomy with lymph node excision].

In 908 radical hysterectomies including dissection of pelvic lymph nodes, 13 (= 1.43%) urogenital fistulas were seen. They occurred postoperatively between the 7th and 15th day. In 12 cases it was a uretero-vaginal and once a vesico-vaginal fistula. The operation report of 7 cases with uretero-vaginal fistula reveals difficulties in separating the ureter in its prevesical part proceeding from tumour spread, endometriosis, scar or bleeding. Since 1985 a percutaneous nephrostomy has been performed (5 cases). 4 fistulas were cured spontaneously, one of them had a percutaneous nephrostomy. In all cases, urography was normal. In 7 cases, ureterocystoneostomy had to be performed. This was done once with fixation of the psoas muscle and 6 times according to Boari. All patients were cured without any complications and with an undisturbed drainage assessed 1 year later by urography. 1 patient, who refused any follow-up, died subsequently. The only vesico-vaginal fistula has been closed by Latzko's procedure. In recent years the problems concerning urogenital fistulas resulting from surgery of cervical cancer have receded. However, if patients adopt an offensive attitude against surgical therapy of stage T2b, the rate of incidence of this complication can be expected to increase.

Adult↗
PubMed1992

[Occlusion of a vesicovaginal fistula with Latzko-repair].

UNLABELLED: The Latzko procedure is a well-known method for the closure of small vesico-vaginal fistulas occurring in the vaginal dome after hysterectomy. This method is favoured by gynaecologists. In three Departments of gynaecology, a total of 104 patients were treated. 76% had been referred from other hospitals. 56.7% resulted from gynaecological operations. In 69.2% was a benign and in 28.8% a malignant disease. In only 2 cases, the primary disease remained unknown. RESULTS: In 97 of 104 (= 93.3%) cases, the procedure according to Latzko succeeded at the first attempt. 5 of 7 recurrences were resolved by the second attempt with the same operative technique according to Latzko, signifying a secondary success rate of 98%. There were only 2 notable complications: the one, where a postoperative bladder haemorrhage attributed to anticoagulants, and the second with a bladder stone noticed 11 years after the Latzko procedure. This technique can be performed in 95% of all vesico-vaginal fistulas occurring. The fundamental advantages of its use are: short duration of the procedure, high cure rate and few complications.

Female↗
PubMed1990

[Diagnosis of angiologic function in unilateral leg edema following combined treatment of cervix cancer].

For the clarification of the genesis of a unilateral dropsy of the legs which had appeared in 16 women after operative and radiologic therapy of a carcinoma of the cervix apparative angiological functional investigations were carried out. A slightly diminished plethysmographic drainage volume in a Doppler-sonographically unhandicapped deep venous flow off corresponded to the clinical picture of the secondary lymphatic oedema. The findings were compared with the behaviour of the parameters in thrombosis of the iliofemoral vein and test persons with healthy vessels. Only in two cases a venous component in form of a stenosis of the pelvic veins and a postthrombotic syndrome, respectively, could be objectified. Since the methodology renders possible a differentiation of lymphatic oedema and phleboedema, it is suitable for non-invasive controls of the course and has practical significance in the after-care of female patients with carcinoma of the cervix.

Combined Modality Therapy↗
PubMed1990

[Myofunction in players of wind instruments].

Within the framework of a longitudinal study, tongue function was examined for maximum pressure, force/time ratio and motility with the aid of a force, pressure and impulse transducer in 181 pupils playing wind instruments and 120 control persons. The methods designed for this purpose provided a reproduction of tongue performance during the act of blowing a wind instrument. The results of this study show statistically significant differences between persons who play wind instruments and those who do not and players of other types of instruments. The data derived from these results permit statements about the degree of muscular malfunction among players of wind instruments. Furthermore, they are helpful in the assessment of therapeutic success or failure.

Facial Muscles↗
PubMed1989

[Estrogen and progesterone receptors in mesenchymal structures of the female urogenital tract].

In 37 women being operated on gynecologically small portions of mesenchymatic tissue have been sampled and analysed with respect to the presence and concentration of estrogen and progesterone receptors within the cytosol fraction. The proofs were taken from: ligamentum cardinale, ligamentum sacrouterinum, pubo-vesico-cervical fascia, paracolpium, ligamentum teres uteri, levator muscle and serving as a comparison tissue from fornix vaginae posterior. In the proofs of pubo-vesico-cervical fascia and paracolpium there were no progesterone receptors. In all the other tissues there were as a matter of principle estrogen and progesterone receptors. However from sample to sample there were wide differences with reference to the existence and the concentration of hormone receptors. There was no correlation to the age of life. The results are discussed and compared with those to be found in literature. MeSH: D 12.776.543.750.830.630 Receptors, estrogen G 6.184.154.803.817.349 Receptors, estrogen G 12.803.817.349 Receptors, estrogen D 12.776.543.750.830.700 Receptors, progesterone G 6.184.154.803.817.777 Receptors, progesterone G 12.803.817.777 Receptors, progesterone A 5.360.319.114.170 Broad ligament A 5.360.319.114.803 Round ligament

Adult↗
PubMed1988

[Actinic bladder-rectal-vaginal fistulas].

Combined fistulas between urinary bladder, rectum and vagina are one of the most serious complications after radiation therapy of genital carcinoma in female patients. The prognosis quo ad restitutionem is poor also at the present time. In our material of 25 cases the restoration of complete faecal and urinary continence was achieved in only 5 patients, however with a loss of the ability of sexual intercourse. In 5 cases an ileum conduit combined with an anus praeter was the definitive solution and in 4 further cases the hygienic situation was improved by colpocleisis and vesico-rectal anastomosis, respectively. In the other patients only a palliative and symptomatical therapy was possible because of poor condition, advanced age and unfavourable local situation.

Adult↗
PubMed1979

[Pregnancy and delivery after renal transplantation (author's transl)].

A case report is given on a 21-years-old woman who became pregnant 18 months after renal transplantation. In spite of relatively unfavourable conditions (match 0,25; hypertension) renal function showed a good adaptation throughout the gestation. In the 38. week of pregnancy the woman was successfully delivered of a 2440 g healthy female child by vacuum extraction. There were no effects of the immunsuppressive drugs on the newborn. It is the third case of a successful delivery after renal transplantation in the GDR.

Adult↗
PubMed1979

[Action of some drugs on pressure profile of female urethra (author's transl)].

The action of certain drugs upon the urethra of clinically intact women was studied by measurement of the urethral profile. beta-adrenoreceptor stimulating and blocking agents, such as fenoterol, propanolol, as well as cholinergics, including carbachol and pyridostigmine, failed to exercise any effect on the urethral pressure profile. On the other hand, anticholinergics, such as atropine and N-butylscopolammonium-bromide, diazepam, and chlorpromazine, produced significant decrease in both maximum urethral pressure and maximum urethral closure pressure. N-butylscopolammonium-bromide and chlorpromazine also shortened the functional length of urethra. Drop of all parameters relating to the urethral pressure profile was observed to take place in response to application of succinylcholine. Phentolamine, an alpha-adrenoreceptor blocking agent, then was administered and caused further reduction of those parameters. The pressure values were elevated by ketamine. The above findings are discussed and compared to present concepts published in literature on medicamentous control of urethral function.

Adolescent↗
PubMed1978

[Surgical management of abdominal-wall insufficiency in the female (report on 94 cases)].

A clinical report is given on 94 cases of operative reconstruction of the anterior abdominal wall. There are medical and cosmetic indications. The morphological and functional results of these operations are good. Attending to the contraindications the number of dangerous complications in the postoperative course is low. No case of death was seen.

Abdominal Muscles↗
PubMed1978

[The carbachol test on the determination of detrusor denervation following extended hysterectomy].

Following radical hysterectomy the urinary bladder develops a denervation supersensitivity to cholinergic stimulation. The carbachol-test based on that observation: after filling the bladder with 100 ml sterile saline and subcutaneous administration of 0,004 mg.kg-1 body weight carbachol the course of the intravesical pressure was recorded. Normal bladders respond with a pressure rise non exceeding 15 cm H2O. Between 15 and 20 cm H2O is a suspicous zone. Test results of more than 20 cm H2O indicate a denervated bladder with increasing certainty. 6 healthy women and 50 patients underwent radical hysterectomy were examined. In 20 women measurements before and after the operation were performed. The carbachol-test is semiquantitative only. In patients with bladder dysfunction we found predominant pathological test results. But there is no evident correlation between the level of the test result and the clinical degree of the micturition disturbances. In some cases the effects of the detrusor supersensitivity on the urethra and the ureter were examined. The conditions of the denervated bladder call for caution in the administration of cholinergic drugs.

Carbachol↗
PubMed1977

[Modifications of the height of the palate by orthodontic therapy].

The height of palate was determined on 400 and on 70 subjects treated orthodontically through the use of removable appliances and by extraction therapy, respectively. Initial and final patterns were used for measurements. A measuring method developed by the authors is described. In the majority of cases, decreases in the height of palate could not be observed, which is in contrast with data reported in the literature. There were only slight differences between the two groups of subjects included in this study. The height of palate was found to change independently of the degree of jaw widening.

Cephalometry↗
PubMed1977

[Antenatal diagnosis of a foetal heart block in the 33. week of pregnancy (author's transl)].

In a pregnant woman of 20 years is recorded a foetal bradycardia of 60 beats per minute in the 33. week of pregnancy. The woman too had an influenza. The cardiological examination shows a congenital complete heart block. After spontaneous delivery of a male infant at date the heart block persists for more than 7 months. There are are no malformations; a interdependence with influenza-infection of the mother is not to be proved. The diagnosis of the congenital heart block is rare. Of 40 cases pointed out in the literature only 3 cases has been diagnosed before the 35. week of pregnancy.

Adult↗
PubMed1976

[Primary, multiple neoplasms in gynecologic carcinomas].

Among 4358 malignant tumours of the female genital tract during a period of 15 years (1958 to 1972) there were 108 primary multiple cancers, of them 53 as first tumours prior to and 55 as second tumours during or after genital carcinoma. The different localisations are demonstrated by tables. The number of the second tumours occured after carcinoma of the cervix and the corpus uteri are compared with a calculated rate of incidence. A satisfacting agreement of the levels allows the conclusion: Primary multiple carcinoma determined by accident and corresponds to the general expectation of carcinoma.

Breast Neoplasms↗
PubMed1976

[Electronic urethro-cystometry before and after reconstructive surgery using the Zoedler method].

Electronical measurement of pressure in the bladder and urethra of 9 incontinent women treated by the Zoedler-plastic. A comparison of pre- and postoperative levels yielded the following results: 1. The functional length and the closing-pressure of the urethra show uncharacteristic changes of the levels only. The expected postoperative rise of the levels have not come true. 2. The vesico-urethral quotient at strain (pV max/pU max) is (with the exception of one case) corresponding to the result of the operation. 3. The clinical recovery from incontinence after the Zoedler-plastic is combined with small changes in the pressure-graphs only.

Adult↗