Biomedical subjects

G Migliore

Publications and source records attributed to G Migliore.

13 recordsLinked to original sources

PubMed1997

HIV infection increases the risk of squamous intra-epithelial lesions in women with HPV infection: an analysis of HPV genotypes. DIANAIDS Collaborative Study Group.

We assessed the association between different HPV genotypes, HIV infection, and cervical squamous intra-epithelial lesions (SIL) in 236 women with known HIV serostatus enrolled in a longitudinal multicentric study in Italy. Of these women, 135 were HIV-infected, and were not markedly different from HIV-negative women with regard to demographic characteristics, sexual practices, smoking, or intravenous drug use. We obtained 232 cervical smears suitable for cytological examination and HPV-genotype analysis (134 from HIV-positive women and 98 from HIV-negative women). For 86 HIV-positive and 89 HIV-negative women, the smears appeared normal at cytomorphological analysis. Cytological dysplasia of varying degrees was detected in 48 smears from HIV-positive women and in 9 from HIV-negative women. HPV prevalence, assessed using polymerase-chain-reaction analysis, did not significantly differ between HIV-positive and HIV-negative women. The prevalence of HPV-associated SIL was much greater among HIV-infected women. The most frequently detected genotypes in both groups were HPV 16 and HPV 18. The prevalence of HPV 16 among HIV-positive women was similar to that for HIV-negative women; this was also true for HPV 18. However, in the HIV-positive group, most of these genotypes were associated with SIL. HIV-positive women showed a wider spectrum of genotypes, including non-oncogenic and rare types. An association between SIL and HIV infection was confirmed for all HPV genotype classes.

Adult↗

PubMed1997

[Laparocele after laparoscopic surgery].

The authors have reported two laparocele cases in the place of insertion of the umbilical trocar, on 156 laparoscopic accesses made by them. Both cases took place at the beginning of their experience when the navel fascial breach had not yet been stitched. The authors made an extensive review of the medical literature and have found out that such complication is rare and to prevent it, it is right to stitch the navel fascial defect, being careful for not englobing the epiploon or an intestinal loop in the suture.

Adolescent↗

PubMed1996

[The laparoscopic approach: a technical note].

The authors report their laparoscopic access technique. It has to be considered a variation of the classical closed technique, with the introduction of the Veress needle and the first trocar directly at the level of the fascia which is kept in traction by two Kochers.

Humans↗

PubMed1993

[Multimedia and didactics++. Application to the normal echographic anatomy of the female reproductive system].

It is widely known that US results strictly depends on operators and that each operator follows individual pathways. Therefore the authors have tried to develop high-interactivity tools, allowing the "customization" of learning to the user's demands. Progress linked to microprocessors' technology allowed a wide spread of cost-effective electronic processors with high graphic performances, capable of supporting sophisticated softwares which are useful to develop multimedial programs. Our experiment is aimed at integrating a multimedial management system for US studies, with the training activity of the medical staff US-expert. The system is structured on a hardware platform based on the Motorola microprocessor, class 68040, an application software developed by Apple. The environment for multimedial applications development uses the "Hypercard" interface of graphic presentation, by Apple. The software allows the realization of a multimedial environment of learning, where US images are associated with graphics, drawing and text references. The application allows a multimedial environment of learning for normal eidodiagnostic anatomy of the female reproductive system, where different courses can be followed autonomously. On the basis of a check performed on a group of students, although in a preliminary stage, the combination of conventional didactic material with either a paper or television support, with devices allowing the connection of texts, graphics and images in a dynamic way, proved to be very useful and to allow personal courses of learning, which can be always modified in an interactive way.

Audiovisual Aids↗

PubMed1991

[Anti-Chlamydia psittaci antibodies in a healthy pediatric population].

Psittacosis or ornithosis is a bird disease caused by Chlamydia psittaci which can be transmitted to man. Little is known of the epidemiology of the disease in this region, but occasional cases which have been brought to the authors' attention have prompted an epidemiological study on the subject. The preliminary results indicate a surprising percentage, over 8%, of antibodies in infants and children. This percentage varies little in relation to place of residence, rural or urban, or the presence of animals, but confirms the high risk in parrot-owning households where anti-Chlamydia antibodies are found in 37.5% of children.

Adolescent↗

PubMed1988