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Biomedical subjects

G Mignemi

Publications and source records attributed to G Mignemi.

8 recordsLinked to original sources

[Laparoscopic hysterectomy in the management of endometrial cancer].

Endometrial carcinoma is the most commonly reported gynaecologic malignancy in industrialized countries. Traditionally the surgical treatment of endometrial cancer is total abdominal hysterectomy, bilateral salpingo-oophorectomy, and peritoneal washing cytology. Alternative surgical procedures have been proposed compared to abdominal hysterectomy: increased number of issues about laparoscopy shows the common trend to use this technique. Literature largely described advantages of the laparoscopic procedure compared to abdominal and vaginal surgery. Long-term follow-up series are not available; further investigation into survival and recurrence rates is indicated.

Endometrial Neoplasms↗

[Clinical use of a GnRH analogue in a depot preparation (leuprolide acetate) in patients with surgical indication for uterine fibromyoma].

During 1992 and 1993, twenty-eight women with uterine leiomyomata received GnRH-agonist (leuprolide acetate) for 3 months before hysterectomy or myomectomy. The decrease in uterine volume and secondary anemia with its collateral effects were assessed, then surgical and post-surgical advantages were assessed too. The real advantages of this treatment are studied and distinguished from theoretic advantages.

Adult↗

Labour management. Our experience.

We report a retrospective analysis of 1202 deliveries assisted by the same medical team, evaluating the clinical management of labour and the resulting type of delivery. Examination of the data revealed a gradual reduction in the number of deliveries treated pharmacologically accompanied by a reduction in the incidence of operative deliveries from 16% to 6%. Statistical analysis of the data using X2 test demonstrated a clear correlation between the administration of oxytocin and the incidence of operative deliveries (p less than or equal to 0.001). We believe that the indiscriminate use of oxytocin in labour should be avoided and that the pharmacological and operative management of labour requires precise clinical indications.

Adult↗

[Therapeutic efficacy and tolerance of a new drug, sodium diclofenac, in inflammatory and metabolic rheumatism].

A new antirheumatic, non-steroid drug, sodium diclofenac (Voltaren Geigy) has been experimented in 14 patients aged between 27 and 69 hospitalized at the IInd Medical Division of Enna Hospital. The patients were divided into three groups suffering from: rheumatoid arthritis, scapulohumeral periarthritis, uratic arthritis, and rheumatic carditis in active phase. In almost all treated cases, the drug proved to have good therapeutic effectiveness demonstrated by complete remission or attenuation of clinical symptomatology and by the return to normal or reduction in the various modified biohumoral indices; in all cases treated, good tolerance, absolute lack of side-effects and toxicity. Special attention has been paid to study of possible changes to gastric mucosa by means of careful evaluation of endoscopic and histological findings.

Adult↗