The incidence of IDDM in children in Japan was found to be approximately 6 out of 100,000 in the child population of 6 to 15 years old. This prevalence is very low compared with those in Caucasian countries. Therefore, the history of management of childhood diabetes in Japan is short compared with that of western countries. Three studies which were carried out in Japan are reported and discussed in this report. The complications and prognosis of Type-1 Diabetes in Japan concluded as follows, 1) The long-term outcome of childhood diabetes was very poor. 2) The prevalence of microvascular complications were strongly related to the age of patients and the duration of diabetes. 3) The prevalence of retinopathy was dependent on the degree of diabetic control. But now, in Japan, we are using the intensive insulin therapy universally for childhood diabetes, and during recent ten years, the management and education of patients progressed rapidly. Therefore, the prognosis of childhood diabetes in Japan will improve.

Adolescent↗

PubMedDate not supplied

Frequency of diabetic nephropathy in childhood diabetics in southern districts of Kyusyu.

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Adolescent↗

PubMedDate not supplied

Study on lipid and glucose metabolism in patients with vasospastic angina.

The primary purpose of the present study was to evaluate the role of lipid and glucose metabolism in vasospastic angina. A group of 93 patients in whom the presence of ischemic heart disease was suggested, were classified into the control (C) group, consisting of 30 patients; the coronary artery disease (CAD) group, consisting of 47 patients; and the vasospastic angina (VSA) group, consisting of 16 patients. Among these three groups, age, total cholesterol (TC), triglyceride (TG), HDL-cholesterol (HDL-C), atherogenic index (AI), apolipoproteins and the prevalence of diabetes mellitus were compared. No age difference was seen among the three groups. The TC was the highest in the CAD group, followed by the VSA and C groups. A significant difference in TC was noted between the C and CAD groups and the C and VSA groups. TG levels were higher in the CAD group than in the C and VSA groups, without a significant difference among the three groups. The AI was significantly higher in the CAD group than in the C and VSA groups. No significant difference was noted in the prevalence of diabetes mellitus among the three groups. Apolipoprotein A-I (apo A-I) levels were higher in the VSA group than in the C and CAD groups, and the difference between the VSA and CAD groups was significant. Apolipoprotein A-II (apo A-II) levels were significantly higher in the VSA group than in the C and CAD groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Angina Pectoris↗