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Biomedical subjects

G Mishra

Publications and source records attributed to G Mishra.

49 records · Page 3Linked to original sources
PubMed1989

Effect of methylene blue and cobaltous chloride on the alloxan-induced changes in collagen characteristics in the skin of garden lizard Calotes versicolor.

In the present study the effect of two chemicals such as methylene blue and CoCl2 on the accelerated ageing of collagen in alloxan-diabetic lizards has been tested. Both methylene blue and CoCl2 have been found to accelerate the ageing of collagen in normal lizards. While methylene blue enhanced the effects of alloxan in alloxanized lizards, CoCl2 tended to reverse it. It appears that methylene blue acts as a potentiator of alloxan; CoCl2, on the contrary, showed clear anti-ageing effects.

Aging↗
PubMed1989

Characterization of non-linear behaviour of an animal membrane using electro-kinetic studies.

Electro-kinetic studies of water, aqueous solutions of urea, thiourea, glucose, creatinine and urine solution across urinary bladder membranes of goat have been used to explain non-linear behaviour. It has been found that fluxes are non-linearly related with forces. The structure of the membrane is a decisive factor when the range of driving forces is not too high. Stability of the steady state has also been examined and has been found to remain quite stable even in non-linear regions. The results have been examined using the methodology of non-equilibrium thermodynamics.

Animals↗
PubMed1986

Alloxan-induced changes in the collagen characteristics in the skin of male garden lizards, Calotes versicolor, from three age groups.

Alloxan diabetes in lizards Calotes versicolor, belonging to three age groups, induced decreased levels of percentage of solubility of collagen in dorsal and ventral skin regions after 7 days of treatment. Old lizards showed greater susceptibility to alloxan diabetes than lizards of the young and middle-age groups. There appears to be no correlation between blood-glucose level and accelerated ageing of collagen. It is suggested that, in alloxan diabetes, metabolites formed in the tissues might accelerate the ageing of collagen.

Aging↗
PubMed1983

Acute viral hepatitis with bridging necrosis. Collaborative study on chronic hepatitis.

Bridging necrosis was recorded in 14% of 361 patients with acute viral hepatitis on examination of the liver biopsy. The clinical and biochemical features of acute viral hepatitis with bridging necrosis were compared with acute viral hepatitis with no bridging necrosis (NBN). It was noted that fever of more than 8 days' duration in the preicteric phase, the presence of mild ascites and pedal edema during the icteric phase, increasing or persistently high levels of serum bilirubin even 4 weeks after the onset of the icteric phase and positive hepatitis-B surface antigen were significantly more common in acute viral hepatitis with bridging necrosis. Hepatitis-B surface antigen clearance was slow in this group. The long-term complication of chronic hepatitis was more frequent in patients with acute viral hepatitis with bridging necrosis.

Adolescent↗
PubMedDate not supplied

On the contribution of height to predict lung volumes, capacities and diffusion in healthy school children of 10-17 years.

Lung volumes, capacities, diffusion and alveolar volumes with physical characteristics (age, height and weight) were recorded for 186 healthy school children (96 boys and 90 girls) of 10-17 years age group. The objective was to study the relative importance of physical characteristics as regressor variables in regression models to estimate lung functions. We observed that height is best correlated with all the lung functions. Inclusion of all physical characteristics in the models have little gain compared to the ones having just height as regressor variable. We also find that exponential models were not only statistically valid but fared better compared to the linear ones. We conclude that lung functions covary with height and other physical characteristics but do not depend upon them. The rate of increase in the functions depend upon initial lung functions. Further, we propose models and provide ready reckoners to give estimates of lung functions with 95 per cent confidence limits based on heights from 125 to 170 cm for the age group of 10 to 17 years.

Adolescent↗