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Biomedical subjects

G Moretti

Publications and source records attributed to G Moretti.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Epidemiological study on tremor in the aged].

203 hospitalized old-aged patients were examined for the presence of tremor. This physical sign was found in 58.6% of cases. By far the largest diagnostic category resulted that of essential tremor: 46.7% of all patients investigated and 77.8% of all cases of tremor. The frequency of this type of tremor was found to increase proportionally to age. The conclusion is drawn that also tremor, as well as other neurological signs frequently demonstrable in "normal" old people (for example, the so-called primitive reflexes), should be inscribed in the group of the phenomena due to the ageing process itself.

Aged↗
PubMed1982

[Disturbances of equilibrium in the aged].

The occurrence during the last year of vestibular disorders, faints and drop attacks was investigated in 150 patients consecutively admitted to a geriatric hospital. The clinical features of these episodes were recorded by means of a proper questionnaire. True vertigo and/or feeling of unstable equilibrium were referred by 54,6% of the patients inquired into, whereas episodes interpretable as faints and drop attacks showed by far lower prevalences, respectively 13,3% and 6%. The Authors call attention to the difficulties in differential diagnosis among these three kinds of phenomena in the current practice.

Aged↗
PubMed1981

[Carotidynia].

The clinical definition of carotidynia is not a controversial one, whereas how its etiology should be interpreted is still uncertain. The study of the clinical features and the therapeutical results in 12 patients suffering from carotidynia reveals a marked resemblance to migraine. In particular, the case history reported points out a significant incidence of migraine as a familial disease, its special localization and the type of pain, the possible presence of a prodromal stage and the favourable response to the drugs that are known to be effective in migraine treatment. The theory that carotidynia should be ascribed to the group of vascular headaches is therefore suggested.

Adult↗
PubMed1981

[A case of multiple cerebrovascular and migraine episodes caused by the use of oral contraceptives].

The Authors report the case of a 32-years-old woman taking oral contraceptives for twelve years, who developed multi-infarct dementia and motor-sensory signs as a consequence of repeated cerebrovascular episodes associated with migraine-like attacks. Neuroradiological findings suggested vascular pathologic changes. Mechanisms of cerebro-vascular diseases related to oral contraception are discussed, especially emphasizing the possibility of intrinsic vascular lesions caused by exogenous steroid stimulation. Epidemiologic and pathophysiological relationship between migraine, stroke and oral contraception are also pointed out.

Adult↗
PubMed1981

[Clinical and electroencephalographic aspects of confusional migraine in adults].

The unusual association of acute confusional states with migraine was observed in three adult women. This syndrome, which was previously studied in the content of juvenile migraine, seem to have the following distinctive features: a) sudden onset of confusion and agitation in the course of violent headache attacks; b) possible close relationship with neurological deficits, suggesting basilar migraine; c) demonstration of marked electroencephalographical abnormalities in either one or both posterior quadrants; d) tendency to a rapid recovery, on both clinical and electroencephalographical standpoint. Focal edema in the vertebrobasilar arterial territory appears to be the most likely mechanism.

Adult↗
PubMed1981

[Comparative study of the frequency of 6 primitive reflexes in a hospitalized population of aged patients].

110 elderly patients, 57 with and 53 without acquired neurological lesions, were examined for the presence of the grasping, snout, sucking, palmomental, glabellar and bulldog reflexes. The results were statistically analyzed by means of the chi2 method. The percentages of the positive reflex responses, although not negligible in the neurologically healthy patients, turned out far higher in the patients with organic cerebral disorders. With the exception of the sucking and palmomental reflexes, these differences appeared statistically significant. As for the neurological diagnosis, diffuse lesions proved themselves more crucial than focal ones. The conclusion is drawn that primitive reflexes should be regarded abnormal only in the context of an overt cerebral pathology.

Aged↗
PubMed1979

Analysis of natural corticosteroids in adrenal extracts and in biological fluids by high-performance liquid chromatography.

A liquid chromatographic procedure is described for the analysis of the principal natural corticosteroids in extracts of adrenal glands. Microparticulate silicic acid columns and gradients of methanol in chloroform are used: conditions are described for the quantitative analysis of the single principal steroidal components of adrenal extracts for pharmaceutical use and of adrenal extracts of rats. In the last case, the use of a 5-micron silica column with the appropriate gradient allows the determination of corticosterone and of 18-hydroxydeoxycorticosterone, which were identified by means of mass spectrometry on their eluates. A single analysis can be performed on the extract of 15 mg of rat adrenal tissue. For the last type of analysis, isocratic conditions on a 10-micron LiChrosorb Diol column are also described. The application of the gradient elution procedure to the analysis of steroidal compounds in human plasma is also described.

Adrenal Cortex↗