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Biomedical subjects

G Morone

Publications and source records attributed to G Morone.

At least 19 recordsLinked to original sources

[Pyogenic liver abscess: a caseload contribution].

Pyogenic hepatic abscesses have been recognized since the time of Hippocrates, but an understanding of their etiology, bacteriology, diagnosis and treatment is an event of the twentieth century. Fortunately mortality rate has declined due to improvements in diagnosis, intensive care, medical and surgical management. In particular, the use of CT and ultrasound scanning has reduced the incidence of unrecognized and therefore untreated liver abscesses. Considering nine patients operated on for liver abscess, the Authors affirm that laparotomic surgical drainage is still the most effective therapy in the majority of cases.

Adult

[The diagnostic elements and therapy principles in thyroid cancer: the Pavia experience 100 years after Bottini].

The diagnostic and operative management of thyroid cancer is controversial as the nature of the disease is heterogeneous in its growth rate, pattern of spread, and histological type. Therefore, surgery must be extensive enough to minimize the chances of recurrence and death. In the period 1962-1989, 159 thyroid cancers were observed. According to the histological type, 61 total thyroidectomies, 34 hemithyroidectomies with isthmusectomy, and 29 subtotal thyroidectomies were performed. Cervical lymph node dissection was performed in 55 patients. The 10-year postoperative survival rate was 70.59% with lymphadenectomy and 65.71% without lymphadenectomy.

Female

The potential malignancy of eccrine spiradenoma.

Eccrine spiradenoma is a rare, usually benign tumor, originating from cutaneous sweat glands. Its clinical and histologic diagnosis can be difficult at times, especially when malignant features are present. Proper management requires radical surgical excision. Two cases of spiradenoma are reported, one of which highly malignant with diffuse pulmonary metastases leading to the patient's death in spite of repeated radical surgery.

Adenoma, Sweat Gland

Genetic heterogeneity in uveitis.

Eighty-nine unrelated patients with ocular inflammation (uveitis) were investigated for the HLA class I and class II genetic markers, We subdivided our patients according to: 1. the anatomical location of the lesion; 2. the temporal course of the disease; 3. the aetiology. We eliminated from our sample of patients the individuals with other systemic diseases. We could not find an association with B27, as previously described, but we did note statistically significant differences between the class II antigen distribution in the different anatomical subgroups. HLA-DR3 seems a marker of the intermediate form of uveitis (p, uncorrected 0.03); the absence of DR1 in the patient group with posterior uveitis may be a protecting factor (p. uncorrected less than 0.01); the presence of DR4 in all cases of panuveitis is statistically significant (p, uncorrected = 0.0006).

Adolescent

[Angiomorphology of the ciliary body in diabetic disease].

The authors describe the pathological changes in the vascular structures of the ciliary body occuring in diabetes mellitus. The lesions consist of a quantitative reduction in the number of vessels and in modifications of diameter and arborisation. Changes include sectoral thinning, isolated and grouped aneuryms and marked tortuosity. These findings are thought to be constant in the diabetic patient and are probably involved in the various aspects of diabetic eye disease affecting other structures besides the ciliary body. The group of vascular changes in the ciliary body in diabetes may aptly be termed "diabetic ciliopathy".

Aqueous Humor

[Blood circulation of the optic nerve with respect to the development of glaucomatous papilla excavation].

Recent research findings in microvascular anatomy enable the authors to make as new suggestion regarding the arrangement of the intraorbital vasculature of the optic nerve. In anatomical specimens three separate zones can be identified, sharply delimited and each with its own source of blood supply. After briefly describing the vasculature of the distal segment (neck) of the optic nerve the authors report several new theories concerning the pathogenesis of glaucomatous cupping of the optic disk.

Glaucoma

[Examination of the venous system of the uvea (author's transl)].

The authors examined the microvascular venous aspects of the uveal membrane and have divided it into three territories: anterior, intermediate and posterior. They showed a double drainage system of the anterior territory. In addition, they believe that there is a difference between the anterior and the intermediate territories, which show sectorization, and the posterior venous territory which presents morphological and functional homogenity.

Animals