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Biomedical subjects

G N Andreev

Publications and source records attributed to G N Andreev.

16 recordsLinked to original sources
PubMed1994

[Rheologic changes of blood in portal hypertension].

The role of hemorheologic disorders in the pathogenesis of portal hypertension in shown. Rheologic disorders are characteristic of both intrahepatic and extrahepatic forms of portal hypertension. It was found that the rate of hemolysis, disorders of the lipid composition and conformation of red cell proteins is reduced in cirrhosis of the liver complicated by portal hypertension. Changes in the portal system microvessels are attended by microcirculatory disorders which are aggravated by changes in the properties of the cell membrane caused by disorders of the blood physico-chemical properties. Purposeful correction of the hemorheologic disorders has a positive effect on the rheologic parameters only in 3-4 weeks. Postoperative complications occur most frequently on the 10th-14th day. A recurrence of acute hepatic insufficiency is also noted at this time in most patients after drainage of the thoracic duct in aggravation of blood rheology. Direct changes of blood rheology in the portal system were revealed, which is a manifestation of the continuously active mechanism of the syndrome which may cause thromboses and massive hemorrhage.

Adult↗
PubMed1985

[Treatment of patients with portal hypertension complicated by resistant ascites].

Indications, volume and technique of surgical procedures in patients with portal hypertension complicated by ascites are discussed. Original methods of external autoreinfusion of the ascitic fluid and peritoneo-jugular shunts are described. It is shown that the surgical measures of treatment of such patients must be gradually complicated from external ascitoreinfusion to intraperitoneal decompressive procedures.

Adolescent↗
PubMed1983

[Crohn's disease].

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Acute Disease↗
PubMed1981

[Acute omentitis].

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Acute Disease↗
PubMedDate not supplied

[A possible complication of therapeutic plasmapheresis].

Possibility of citric intoxication as a complication of therapeutic plasmapheresis is being discussed on the basis of two clinical observations. Hemodynamic reactions to sodium citrate administration have been noted during reinfusion of auto red cell mass. It is suggested that the development of collapsoid reaction, accompanied by a significant decrease in the total peripheral resistance at a stable cardiac output and cardiac index, is determined by the transition of the ionized calcium of the blood into calcium citrate, and thus the violation of the processes regulating the excitement and constriction of the muscular cells in the peripheral arteries. On the basis of further observations (360 therapeutic plasmapheresis procedures) gradual injections of small calcium quantities are recommended for the prevention of citric reactions during reinfusion of auto red cell mass.

Adult↗
PubMedDate not supplied

[Comparative characteristics of the lipid composition of lipoproteins of the blood plasma and ascitic fluid in liver cirrhosis].

Comparison of phospholipid content in different fractions of lipoproteins of the ascitic fluid and blood plasma showed selective accumulation of high density lipoproteins (HDLP) in the ascitic fluid. The ascitic fluid HDLP differed from blood plasma HDLP in a larger fraction of triglycerides and cholesterol oleate. No significant difference was revealed in the lipoprotein (LP) low density lipid spectrum in the two fluids. The very low density LP (VLDLP) of the ascitic fluid differed from blood plasma VLDLP by higher ratios of phosphatidylcholine (PC) (sphingomyelin and PC) unesterified cholesterol; the PC in VLDLP of the ascitic fluid had a relatively higher content of linoleic and oleic acids. It is suggested that the detected differences are associated with dynamic insufficiency of lymph drainage in portal hypertension, as the result of which LP of intestinal genesis, spreading in the interstitium of the wall of the small intestine, enter the abdominal cavity by bypassing the blood plasma.

Ascitic Fluid↗