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Biomedical subjects

G N Nobre

Publications and source records attributed to G N Nobre.

5 recordsLinked to original sources
PubMed1987

The oxidase test in yeasts of medical importance.

The results of an oxidase test were positive with species of Cryptococcus and eight species of Candida, but negative with Candida krusei and species of Saccharomyces and Torulopsis, grown on Columbia Agar base and similar media, including Brain Heart Infusion Agar and Mueller Hinton Agar. When grown on Sabouraud Dextrose Agar, all the yeast genera and species were oxidase negative. The test is useful in delineating the genus Candida from Saccharomyces and Torulopsis.

Candida↗
PubMed1986

Enhancement of Streptococcus faecalis infection and complement depletion in yeast-treated mice.

Enhancement of Streptococcus faecalis infection and lowering of the complement level have been demonstrated in mice injected with a heat-treated suspension of baker's yeast (Saccharomyces cerevisiae). The leucocyte response to the infection was not affected. The yeast preparation showed, in vitro, an intense anti-complementary activity on mouse serum and interfered with the microbial killing function of the mouse peritoneal macrophages. No significant stimulation of the growth of S. faecalis in vitro in the presence of the yeast was observed. The enhancement of the infection in mice treated with the yeast seems to be mediated, mainly, by complement depletion.

Animals↗
PubMed1982

Identification of Haemophilus ducreyi in the clinical laboratory.

Some of the characteristics of 42 clinical isolates of Haemophilus ducreyi are reported. Only six of the 42 strains were able to grow on horse-blood agar. All strains gave a positive oxidase test with tetramethyl-p-phenylenediamine and a negative result with dimethyl-p-phenylenediamine. All of 15 test strains were negative in the porphyrin test. Tests for haemin requirement were inconclusive because of difficulties encountered in obtaining growth on a basal medium.

Adolescent↗
PubMed1980

In vitro development of resistance to nystatin by Candida albicans and Torulopsis glabrata.

The levels of resistance to nystatin induced in 16 strains of Torulospsis glabrata by a few subcultures in the presence of the drug were high (minimum inhibitory concentrations > 20 000 U ml-1) compared with those obtained in 12 strains of Candida albicans (minimum inhibitory concentrations less than or equal to 2000 U ml-1). The results suggest a high rate of mutation in the first species.

Candida↗