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Biomedical subjects

G Nathan

Publications and source records attributed to G Nathan.

32 records · Page 2Linked to original sources
PubMed1983

Head and body hemispace to left and right III: Vibrotactile stimulation and sensory and motor components.

Response latencies were measured to vibrotactile stimulation delivered to the forefingers of the left or right hands which were positioned ipsilaterally or contralaterally (across the midline) in left or right hemispace. While the two hands did not differ in speed of response, either hand performed better when located in right hemispace (experiment 1). This effect was greatly reduced, though not eliminated, with 90 degrees lateral head turn, when performance was better with stimulation and responding in right-of-head hemispace, but not right-of-body hemispace (experiment 2). When different hands received stimulation and initiated responses, and were located in either the same or opposite hemispace, right-hemispace superiority was found to be motor rather than sensory (experiment 3). These findings are discussed in the context of the true and the phenomenological midline and the clinical syndrome of hemineglect.

Adult↗
PubMed1983

Loiasis in an American naturalist.

In March 1981, a 32-year-old male naturalist involved with collecting mammals for study was found to have an unexpected eosinophilia. Serum parasitic screening done at the Centers for Disease Control showed filarial titer by indirect hemagglutination of 1:1,024 and of 1:40 by bentonite flocculation. His travel history disclosed 3 months spent in Cameroon in 1978. He also gave a history of intermittent arm swelling for at least a year. Peripheral blood, collected repeatedly at mid-day and midnight and tested for microfilariae by the Knott technique, was negative. He was begun empirically on diethylcarbamazine, and on day 11 of treatment he removed a worm, identified as a male Loa loa, from his leg. He completed treatment without difficulty and has done well.

Adult↗
PubMed1975

Imipramine-caused interference with levodopa absorption from the gastrointestinal tract in rats.

Rats treated for 3 or 30 days with imipramine (30 mg/kg) have impaired absorption of a single dose of 14C-levodopa. Treated animals retain larger amounts of radioactivity in their gastric lumen and this interfers with delivery of levodopa to intestinal absorptive sites. Tissues of treated animals have lower levels of radioactivity than controls and urinary excretion of radioactivity is also lessened. Imipramine does not interfere with uptake of levodopa by everted sacs of rat jejunum. Imipramine does, however, interfere with the transit of radioactivity through the gastrointestinal tract of rats, since treated animals have lower ileal radioactivity than controls. Lower relative concentration of levodopa metabolites in gastric fluid and tissue may reflect an interference of uptake of levodopa by gastric enterochromaffin-like cells.

Animals↗