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G Neverre

Publications and source records attributed to G Neverre.

13 recordsLinked to original sources

[Experimental study of the sensitivity to catecholamines after lumbar sympathectomy (author's transl)].

To determine sensitivity to catecholamines after lumbar sympathectomy the authors first tested it in dogs : there was an increase in reactions to catecholamine beyond doubt after bilateral lumbar sympathectomy. In patients with arteritis they recorded, on a segment of the lower limb, a rheographic tracing with simultaneous modifications of the arterial blood pressure and electrocardiogram. These were studied after injection of adrenalin or noradrenalin in a dose of 5 to 7.5 mug (physiologic or stress level). Each of these tests were performed before and after lumbar sympathectomy.

Animals↗

[The normal reaction of sinocarotidian origin in the rabbit].

Spontaneous changes of respiratory rate and blood pressure in the slightly anesthetized rabbit, contemporaneous with hippocampal synchronization, might be related with abrupt changes of the alertness. Registration of arousal reaction in hippocampal, thalamic and cortical leads, elicited by Hering nerve stimulation, shows that baro- and chemosensitive afferences may induce activation of areas which are usually involved in conditioning process.

Animals↗

[Autotransfusion in experimental hemoperitoneum. Hematologic study].

In order to study the hematologic repercussions of pre-operative autotransfusion, ruptures were made in experimental spleens followed by retransfusion after intraperitoneal barbotage of long duration in 8 dogs. This was performed without any heparinization. The following facts could be established:--although the blood shed was rich in red globules, it presented major alterations with a loss of clotting agents and evidence of fibrinogenic degradating elements.--A study of the blood during the transfusion and after the intervention did not reveal any intravascular coagulation but only a loss of fibrinogen and thrombocytes proportional to the amount of autotransfused blood. The limit of haemostatic tolerance with no supply of external blood was an autotransfusion ranging about 75 p. 100 of the initial blood volume.

Animals↗

Experimental study of sensitization to catecholamines after lumbar sympathectomy.

In a first time, the authors have shown a real supersensitivity to the action of catecholamines after lumbar sympathectomy in dog. Then, they have established a protocol which can be applied to the exploration of those phenomena in arteritic patients. Same doses of epinephrine and norepinephrine (which correspond to a slight hypercatecholamine blood level under stress) are injected intravenously, comparatively before and after lumbar sympathectomy. The modifications of E.C.G., arterial blood pressure and rheographic record, caused by those injections seem to prove the existence of a sensitization which is still lasting 4 months after the operation, but which does not seem to be noxious. Therefore, this sensitization generates compensating reflex reactions to arterial hypertension, leading to a favorable increase of the blood flow in the denervated territories.

Animals↗