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Biomedical subjects

G Ninane

Publications and source records attributed to G Ninane.

At least 19 recordsLinked to original sources
PubMed1983

The in vitro activity of ceftazidime against a multi-resistant serotype 12 Pseudomonas aeruginosa.

Highly resistant isolates of Pseudomonas aeruginosa serotype 12 accounted for 42.2% of the pseudomonads isolated from patients in a 600-bed hospital over a period of 18 months. In vitro studies showed that this organism was resistant to tobramycin, gentamicin, apalcillin, piperacillin, azlocillin, ticarcillin, cefotaxime and cefsulodin. All serotype 12 isolates were completely sensitive to ceftazidime. Its geometric mean MIC was 3.4 mg/l. This new cephalosporin seems promising for the treatment of patients infected with pseudomonas, especially when a resistant strain such as serotype 12 is involved.

Anti-Bacterial Agents↗
PubMed1978

Bronchopulmonary infection due to Branhamella catarrhalis: 11 cases assessed by transtracheal puncture.

Transtracheal punctures were performed in 193 miners of anthracosilicotic coal who presented with an acute exacerbation of chronic bronchitis. The transtracheal aspirates were bacteriologically positive in 104 patients. Branhamella catarrhalis was isolated in 15 patients; 10 of these responded to chemotherapy, as shown by the resolution of all symptoms and the disappearance of the organism on a repeat transtracheal puncture performed 48 hours after the end of treatment. One ampicillin-treated patient, whose bronchial secretions yielded a beta-lactamase-producing B catarrhalis, showed no improvement. But subsequent treatment with cefuroxime was followed by clinical and bacteriological recovery. B catarrhalis probably acted as an opportunistic respiratory pathogen in these patients, who were probably compromised hosts in view of their clinical history. B catarrhalis normally responds to the penicillins commonly used for respiratory infections, but if treatment fails a transtracheal puncture is essential to identify the strain and determine an appropriate antibiotic.

Ampicillin↗
PubMed1978

[Autologous blood transfusion in a department of gynaecological surgery].

A single unit of 350 ml of whole blood was drawn 8 days before surgery, from 50 patients of a gynecological clinic. Hysterectomy was performed in 44 cases. Haematological values did not show any significant modification and no side effects attributable to the phlebotomy was detected before or during surgery. In 88% of cases, the utilisation of autologous blood has avoided an homologous transfusion whose side effects are well known.

Adult↗