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Biomedical subjects

G Noel

Publications and source records attributed to G Noel.

70 records · Page 4Linked to original sources

Ultrasonographic determination of residual urine in diabetic subjects: relationship to neuropathy and urinary tract infection.

The presence of residual urine was determined by postvoid bladder ultrasonography in 37 control subjects and 102 unselected insulin-dependent and non-insulin-dependent diabetic patients. Significant residual volume was detected in 19 diabetic subjects without explanation other than diabetic neurogenic bladder dysfunction in 15. The four others had prostatic hypertrophy. Excluding these four subjects, those with residual urine were slightly older than the others (P less than 0.05), but the known duration of diabetes was increased only for the insulin-dependent group (P less than 0.05). The presence of residual urine was strongly associated with peripheral neuropathy (P less than 0.001). In contrast, of all the manifestations of autonomic failure studied, only impotence (P less than 0.01) and decreased pupil motility (P less than 0.05) were associated with residual urine. The prevalence of urinary tract infection was higher in women than in men (P less than 0.02). This prevalence was increased in the presence of residual urine (P less than 0.02) but only for men (P less than 0.001).

Adult↗

[Risk factors of non-proliferating retinopathy in insulin-dependent diabetes].

Risk factors for non proliferative retinopathy were investigated by comparing two groups of insulin dependent diabetic patients: group NR of 25 patients without retinopathy and group R of 25 patients studied at the time of discovery of non proliferative retinopathy. The two groups were matched for age, sex and diabete duration. They were significantly different for insulin treatment regimens, blood glucose control and blood pressure. Lipid parameters and renal function were similar in the two groups.

Adult↗

[Quantitative rheoencephalographu in normal and pathological ageing (author's transl)].

A method of quantitative rheoencephalography estimating the rapid cerebral blood flow, defined by the clearance of Xe 133 is applied to normal, hemiplegic and demented subjects. In the normal child the flow is twice that of the elderly. In adults a decrease of 13% is observed in the fifties. The flow is decreased in both hemispheres of the hemiplegics. The cerebral flow is decreased in the two clinical groups of demented patients (vascular and non-vascular); different values of flow are obtained in these two groups.

Adolescent↗

[Value of the probenecid test in the diagnosis and treatment of parkinson disease].

Forty-five patients presenting a parkinsonian syndrome, accompanied in some cases by depressive and/or confusional signs, were subjected to neurological and neurobiochemical investigation involving a probenecid test (estimate of central turnover of dopamine by determination of homovanillic acid in cerebrospinal fluid before and after an oral dose of probenecid). Patients were classified in two groups on the basis of the benefit procured by dopa therapy as estimated at least one year after treatment. The probenecid test revealed a sharp drop in turnover of dopamine in the dopasensitive group. Furthermore, in this group the dopamine turnover was not related to sex, age, duration of the parkinsonian syndrome or clinical severity. In contrast, there seemed to be a correlation between dopamine turnover and optimum dosage of l-DOPA. Lastly, the study showed that, beyond the diagnosis of dopasensitivity, the test was useful for patient follow-up. The test profile in cases of excess dopatherapy is described.

Aged↗

[A case of post-hepatitic Guillain-Barré-Strohl syndrome with extension to all pairs of cranial nerves and late papilledema. Review of recent literature (author's transl)].

The authors report the case of a 17 year-old female patient who presented acute ascending polyneuritis of the Landry-Guillain-Barré type extending to all cranial nerve pairs during the abatement of hepatitis of unspecified etiology. The patient remained in a state of coma vigil for five days prior to gradual but full recovery over a six-month period. The patient was given respiratory assistance for 55 days, together with corticosteroid therapy and above all plasmapheresis. After five weeks of treatment a transient late papilledema was noted for about six weeks. The authors discuss the diagnostic criteria of the Guillain-Barré-Strohl syndrome, its etiology, the possibility of central nerve involvement and late papilledema. Treatment with corticosteroids and plasmapheresis is also discussed.

Adolescent↗