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G Nowicki

Publications and source records attributed to G Nowicki.

8 recordsLinked to original sources
PubMed2000

[Ultrasonographic assessment in differential diagnosis of non-palpable breast tumors].

In this study we analyse the value of high frequency ultrasound as diagnostic tool in non-palpable breast nodules (NPBN). We selected 121 women with NPBN revealed by ultrasound (US). The size of the nodules varied from 3 mm to 32 mm. Women with NPBN detected by US underwent sonographically-guided fine-needle aspiration biopsy (FNAB) and/or histological examination. Based on the US examination findings, the disease was diagnosed as malignant in 6 cases, as benign in 90, and in 28 cases it was unclassified. 15 patients underwent surgery. In 8, the disease was histopathologically confirmed as carcinoma (US 2 unclassified), 7 were benign lesions. US with FNAB as tool in diagnosing NPBN is an accurate technique for distinguishing between benign and malignant NPBN observable sonographically.

Adult↗
PubMedDate not supplied

Can we suspect fetal down syndrome by heart evaluation during the second half of pregnancy?

UNLABELLED: Thirty fetuses with Down syndrome, who had detailed fetal echocardiography and sonography at the tertiary center with videotape recordings, were retrospective analyzed by one observer with a specially prepared flow sheet. The mean gestational age of the fetuses at the time of the study was 31 +/- 5.6 (minimum 21, maximum 39) weeks. The 'main' fetal abnormalities were congenital heart defect (CHD): in 13 cases (43.3%) an abnormal 4-chamber view was recorded, including 6 cases (20%) of isolated CHD and 7 (23.3%) of coexisting CHD + extracardiac malformation. Of the 13 cases of CHD, there were 12 cases of atrio-ventricular canal and 1 case of ventricular septal defect. Normal heart anatomy was recorded in 17 cases (56.7%), including 2 with tricuspid value regurgitation. From the videotape recordings also some 'minor' abnormalities were noticed in a few cases such as: femur length shortening; sandal gap; pericardial effusion; macroglossia; echogenic bowel; absent diastolic flow in the umbilical artery, and others. The prevalence of CHD in the study group was similar to the prevalence of CHD in the comparison group of 20 newborns with Down syndrome, born during the same period of time at the same institution, who had not had prenatal scanning at all (chi2, p > 0.05). CONCLUSIONS: (1) the main 'major' abnormality which might be detected in a fetus with Down syndrome after 20 weeks of pregnancy is CHD, which was presented in 43.3% of this series; (2) the presence of any extracardiac malformation should prompt the sonographer for detailed heart evaluation, and (3) fetal echocardiography may increase the accuracy of 'genetic sonogram' in Down syndrome.

Adult↗
PubMedDate not supplied

[Hypoplasia of Leydig's cells as a cause of male pseudohermaphroditism].

A case of male hermaphroditism is presented. It complied with all traditional criteria of male hermaphroditism due to Leydig's cells hypoplasia (anomaly of the internal genitalia, karyotype 46, XY, presence of the testicular tissue, no response of the hypoplastic Leydig's cells to HCG stimulation with simultaneous dramatic decrease in their number in the interstitial tissue. Emphasis is on the marked difference in incomplete virilization of the external genitalia related to the occurrence of Leydig's cells insufficiency.

Adult↗