Biomedical subjects
G O Hopkins
Publications and source records attributed to G O Hopkins.
Exercise induced injuries--the way ahead.
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Stress fracture in parachute regiment recruits.
A survey of stress fractures occurring in recruits at the Depot of The Parachute Regiment was carried out over a one year period from July 1985 to August 1986. A total of 44 fractures in 36 soldiers were diagnosed. The incidence was thus 4.84%, much lower than that found in a recent prospective Israeli study. Only one case of progression to complete fracture was observed during the study. In contrast to the previous experience with British recruits, the commonest site of stress fracture was the tibial midshaft.
Rubella-associated bleeding diathesis presenting with a haemarthrosis.
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Lone axillary nerve lesion due to closed non-dislocating injury of the shoulder.
Two rugby players with a lone axillary nerve lesion are described. Neither suffered an overt dislocation of the shoulder nor was there any evidence of severe local injury. Recovery in both was complete by 1 year. Possible mechanisms of injury are discussed.
Muscle changes in ankylosing spondylitis.
Muscle biopsy of the quadriceps femoris was carried out in 20 patients with classical ankylosing spondylitis (AS). Histological and histochemical studies revealed changes in all biopsies to a varying degree. Central migration of nuclei was present in 80%, reduced fibre size with some atrophy in 40%, localized reaction to acid phosphatase in 75% and a peripheral condensation of reaction product to NADH-TR stain in 55% of biopsies. Furthermore 14 out of 16 patients, whose quadriceps strength was measured, were found to be below the predicted values, when compared to healthy controls of similar weight, and quantitative surface electromyography in 10 showed lower mean power frequency than in controls. A raised plasma creatine kinase was found in only two patients. It is concluded that muscle changes occur in AS and these may account for some of the clinical features of the disease.
Multiple joint tuberculosis presenting as HLA-B27 disease.
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The development of a co-location system for the treatment of the severely brain damaged.
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