Biomedical subjects
Publications and source records attributed to G O'Dell.
The first step in planning is to assess your environment. Ask the long-range questions: What does your current market look like? What are the demographic trends that will influence your community? How will the workforce issue and the regulatory environment affect your hospital? Hospitals & Health Networks presents the American Hospital Association's environmental assessment, which may help you to conduct your own.
Three to 4 cm-diameter, circular-shaped full thickness sections of the anterior wall of canine bladders were resected. Free grafts of bladder mucosa were lifted from the muscular wall and sewn back as a patch onto the original defect. Fusion of the graft and normal urothelium occurred, and at eight weeks a dense fibrotic external layer and normal urothelium was observed. No diverticuli occurred. A successful closure of recurrent multiple vesicovaginal fistulas in a woman using mucosa alone is reported.
Free patch grafts of bladder mucosa and underlying lamina propria have been used to cover large defects in canine bladder walls. Both autografts and allografts were successfully transferred. Sex chromatin studies showed the final urothelial covering was from the recipient and not the donor bladder.
Free bladder mucosal grafts were evaluated as material for ureteral substitution. Surgical replacement of the ureter with free bladder mucosa in dogs demonstrates the feasibility of this technique. Graft patency with preservation of urothelial lining and regeneration of smooth muscle was observed. Physical properties observed during the experiment indicate a good potential for long term preservation of the graft material.
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