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Biomedical subjects

G Obeid

Publications and source records attributed to G Obeid.

13 recordsLinked to original sources

Effect of ibuprofen on the healing and remodeling of bone and articular cartilage in the rabbit temporomandibular joint.

The purpose of this study was to determine the effect of ibuprofen on the healing and remodeling of bone and cartilage in the temporomandibular joint of the rabbit. Forty-two rabbits were operated on to create a groove and a hole in the articular surface of both the right and left mandibular condyles. Following surgery, the animals were divided into three groups. Group A (12 rabbits) was used as a control and the animals did not receive any medication. Group B (15 rabbits) was given a daily dose of 17 mg/kg of ibuprofen. Group C (15 rabbits) was given a daily dose of 34 mg/kg of ibuprofen. All animals were killed after 4 weeks. The 84 condyles were examined clinically and histologically. Statistical analysis showed a highly significant difference in the healing of bone and cartilage between groups A and C (P less than .01) and a significant difference between groups A and B (P less than .05). The results of this study indicate that ibuprofen has an adverse effect on the healing of bone and cartilage in the temporomandibular joint of the rabbit.

Animals↗

Optimal placement of bicortical screws in sagittal split-ramus osteotomy of mandible.

When a bicortical screw is used for the rigid fixation of sagittal split-ramus osteotomy, by definition the threads of the screw should engage in the buccal plates as well as in the lingual plates. In a study of six dry mandibles we found that when 2 and 2.7 mm screws are used in noncountersunk holes, it is almost certain that a thread will engage the buccal cortical plate. With countersinking 55% of the 2.7 mm and 27% of the 2.0 mm screws had no threads engaged in the buccal cortical plate. This changes these screws from bicortical to compression type. An anatomic study of bone thickness demonstrated that the thickest buccal and lingual cortical plates were in the superior border of the ramus, just distal to the last molar. In addition, a change in the intercondylar distance before and after surgery was observed in every mandible.

Bone Screws↗

A comparative study of the treatment of unilateral fractured and dislocated mandibular condyles in the rabbit.

This study evaluated the results of three methods of managing simulated unilateral dislocated fractured mandibular condyles in the rabbit. The first method consisted of surgical reduction of the fractured condyle to its anatomic position and its subsequent fixation with a titanium plate. The second method differed from the first by completely detaching the condyle, then replacing it as free graft. The third method left the fractured condyle in its dislocated position outside the glenoid fossa. Eighteen rabbits were used, 6 animals for each method. Half the animals in each group were killed at 4 weeks, the other half at 14 weeks postoperatively. Clinical, morphologic, functional, radiologic, and histologic examinations were conducted on all animals. The results indicated that open reduction with internal fixation with no disruption of the blood supply to the condyle provided the most favorable results. While closed reduction without internal fixation gave good functional results, definite reduction in ramus height on the operated site was observed in this group of animals. Animals that had open reduction and internal fixation using the condyle as a free graft did not do as well as the other two groups. Despite good mouth opening and occlusion, more animals showed facial asymmetry and it was more severe. None of the condyles were lost as result of necrosis, but healing took longer when compared with the other group of animals.

Animals↗

Complications of genioplasty done alone or in combination with sagittal split-ramus osteotomy.

Thirty-one patients who had genioplasty done alone or in combination with bilateral sagittal split-ramus osteotomy of the mandible (BSSRO) were examined within 12 to 68 months after surgery. Neurosensory tests revealed that 10% of the mental nerves in patients who had had isolated genioplasties showed altered sensation of the lower lip, compared to 28.5% of the nerves in patients who had genioplasties and bilateral sagittal split-ramus osteotomies. However, when questioned, 71% of the patients in the latter group indicated awareness of abnormal feeling in the lower lip. Fourteen teeth in isolated genioplasty cases gave an abnormal response to electric pulp testing. The incision lines healed satisfactorily in most patients. Of the intraosseous wires used for fixation, 5.38% were removed 3 to 10 months after surgery. A notch at the osteotomy site on the lower border of the mandible was noted radiographically in 72.5% of the sites. Chin ptosis was noted in one patient. The cosmetic results satisfied 93.6% of the patients.

Adolescent↗

Costochondral grafting in condylar replacement and mandibular reconstruction.

Thirty costochondral grafts in 22 patients were retrospectively studied with a mean follow-up of five (range, 2 to 11) years. The functional results, esthetics, and incidence of complications in these patients were determined. A discussion of these findings as well as the surgical technique is included. The results confirm previous studies and indicate that free costochondral grafting is a successful and physiologically sound method for reconstruction of portions of the mandible and its temporal articulation.

Adolescent↗

A simplified method for the internal fixation of fractures of the mandibular condyle.

The morbidity following conservative management of fracture dislocations of the mandibular condyle is considered, and the theoretical advantages of open reduction discussed. The various methods described in the past are reviewed and a new technique is described whereby a Kirschner wire is drilled into the condylar fragment and then inlaid into the ramus. Advantages over previous methods include easy manipulation of the fragment and lack of danger to the facial nerve.

Fracture Fixation, Internal↗