Response of platelets to prolonged physical exercise.
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Biomedical subjects
Publications and source records attributed to G P Fantin.
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This methodological investigation is a formal and short outline of a rheological model for human plasma. Such a model proposal originates from equations and formulae for viscosity of colloidal suspensions and macromolecular solutions established by several authors (R. Simha, G. I. Taylor, W. and H. Kuhn). The model here proposed requires very hard oversimplifications and it may be considered as a semiempirical approach.
A review of 193 cases of invasive carcinoma of the cervix was undertaken to determine the efficacy of the procedures used in the staging of this disease. All patients underwent pretreatment chest, pelvis, and spine radiographies, intravenous pyelogram, cystoscopy and proctoscopy. Bone scanning was performed too. These patients were retrospectively staged according to findings of the physical examination only. Each additional examination was then evaluated comparing its results with the initial staging. The column Xray did never change the stage; the other radiologic examinations changed the staging as follows: chest Xray 0.5%, pelvis 1%, intravenous pyelogram 2%. Cystoscopy and proctoscopy changed the clinical stage in 5.1% and 2.5% of the cases, respectively. Bone scanning in 1.5%. A review of 54 selected cases was undertaken to determine the presence of positive nodes in patients with carcinomas at stages I and II. In 16 cases of cervicocarcinoma the hystologic examination showed positive pelvic lymph-nodes. The AA, recommend all the reviewed procedures in the staging of carcinoma of the cervix in initial stages too.
It was demonstrated that the previous in vitro electrical stimulation of human and rat platelet-rich plasma does not modify the subsequent response of platelets to the aggregating activity of ADP, thrombin, thrombofax or adrenaline. This is interesting in view of the fact that the electrical stimulation can induce clot retraction.
The spontaneous clot retraction of platelet-rich plasma is inhibited by previous in vitro ADP-induced platelet aggregation. The electrical stimulation of the clot always restores a maximal clot retraction, even after a prolonged previous in vitro platelet aggregation.
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