PubMed Health⌕ Search

Biomedical subjects

G P Heilgemeir

Publications and source records attributed to G P Heilgemeir.

5 recordsLinked to original sources
PubMed1989

[The Brocq pseudopelade--a disease picture or disease entity].

In 1885 Brocq described a type of scarring alopecia he called pseudopelade (PPB), whose character as a separate disease entity has been denied in recent decades. Several authors now believe PPB to be a polyetiological final stage (état pseudopeladique de Degos; EPP). In all, 142 patients with scarring alopecia were analyzed in an attempt to find whether PPB is a separate entity or not. Following examination, 26 cases with lichen ruber (LR), 18 cases with lupus erythematosus chronicus discoides (DLE), 2 cases with scleroderma, 1 case with folliculitis decalvans, and 1 case with ichthyosis vulgaris were diagnosed; this left 94 cases with PPB (66%). We attempt to describe the macroscopic morphology and histopathology in PPB and in LR and DLE. The findings yielded by direct immunofluorescence and the treatment are discussed.

Adolescent↗
PubMed1979

[Histological differential diagnosis of psoriasis vulgaris and seborrheic eczema of the scalp].

The clinical differential diagnosis between seborrheic dermatitis and psoriasis vulgaris of the scalp can be difficult. We, therefore, tried to elaborate histopathological criteria for a differentiation of the two dermatoses. Forty excisional biopsies were analysed without knowing the clinical diagnosis. The histopathological substrate within the epidermis is characterized in psoriasis by dermatitis-like and in seborrheic dermatitis by psoriasis-like alterations. Therefore, in some cases a definite histopathological diagnosis could not be made. Strong criteria favouring psoriasis are: moderate condensed hyperkeratosis with alternating parakeratosis, PAS-reactive serum inclusions and Munro abscesses within the horny layer, spongiform pustles and neutrophilic leukocytes within the epidermis. Strong criteria for seborrheic dermatitis are: irregular acanthosis with relatively thin condensed orthoor parakeratotic horny layer, spongiosis and spongiotic vesicles, exocytosis of lymphocytes and the lack of any hard criterias for psoriasis. The results may suggest that seborrheic dermatitis of the scalp may transform into psoriasis in patients with a genetical disposition ("psoriatic diathesis", "latent psoriasis") via a Köbner reaction. The existence of the seborrheic dermatitis (Morbus Unna) is not doubted by these investigations.

Biopsy↗
PubMed1978

[Dandruff (pityriasis simplex capillitii)].

In this review of new studies about dandruff, methods for clinical (subjective) evaluation and quantitative (objective) appraisal of dandruff are described. Current concepts about histopathology, cytology, biochemistry and etiopathogenesis of this common condition of the scalp are detailed.

Adult↗
PubMed1977

[Significance of hair root status method].

The significance of proposition of the hair root status method is reported. The percentage composition of the hair root patterns of neighboring areas of the capillitium and the behavior of the percentage of the individual hair root shapes were examined at time zero and four weeks later. These examinations were carried out in the frontal, parietal and occipital regions of each of 10 male test persons with clinically normal hair growth and statistically evaluated by means of the multi-variate Hotelling T2 test [8]. The hair root pattern of neighboring areas is the same within the different regions of the capillitium (p less than 0.05). Thus the hair root patterns investigated in the different regions of the capillitium are representative of this respective region. The hair root patterns of males with clinically normal hair growth (for the frontal, parietal and occipital region) does not differ with time (p less than 0.05). Therefore, examination of the hair root pattern at four week intervals can be used for controlling the hair growth capacity and therapeutic effects. The significance of the hair root status method for controlling therapeutic effects may be relative small in the individual case in a person with normal hair growth, but useful when evaluated in a collective of subjects.

Alopecia↗