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Biomedical subjects

G P Sala

Publications and source records attributed to G P Sala.

At least 19 recordsLinked to original sources

[Cutaneous angiogenesis associated with vulvar epidermoid carcinoma].

A case of cutaneous angiogenesis, probably induced by tumour angiogenic factors (TAF), is described. The patient, a 39-year-old female, affected by a vulvar squamous cell carcinoma, developed some erythematoangiomatous lesions on the lower abdominal quadrants, contiguously to the tumour. Histopathologically, the lesions were characterized by vascular neoformation in the superficial dermis and a slight lymphohistiocytic lesions resolved after the polychemotherapy which preceded enlarged vulvectomy. This supports the hypothesis of a close correlation between neoangiogenesis and TAF.

Adult

[Trigeminal neurotrophic ulcer. A case report].

A case of a 49-year-old woman affected by wide ulcerations on the face which have been caused by the patient herself, as she has admitted, is reported. The lesions were strictly limited to the area of innervation of the first and second branch of the trigeminal nerve. The patient presented parasthesias and analgesia in the trigeminal area as the consequence of a neurosurgical operation. She also suffered from important psychosis. All these elements enable us to diagnose "trigeminal trophic ulcers". The pathogenesis of this syndrome is discussed.

Cranial Nerve Diseases

[Unilateral nevoid syringoma].

A case of unilateral naevoid syringoma is reported. Syringoma is an adnexal benign neoplasia originating from the ducts of eccrine sweat glands. Localized (neck, anterior portion of the chest, genitalia, fingers) and generalized forms are known, but unilateral naevoid syringoma is quite uncommon. The existence of this variety can be explained with reference to the theory of "genetic mosaicism".

Adenoma

[Gottron's erythroderma congenitalis progressiva symmetrica].

Two patients with erythrokeratoderma are observed, a mother aged 42 and her 16-year-old son. In both cases the dermatosis started on the 40th day after birth and covered slowly and symmetrically the lower and upper limbs as well as the face. The two patients underwent two different treatments: the mother was treated with aromatic retinoid for 8 weeks; the son with PUVA therapy for a total of 63 J/cm2 UVA. With both methods it was possible to obtain good results. However, the results were better with PUVA therapy.

Dermatitis, Exfoliative