PubMed Health⌕ Search

Biomedical subjects

G P Vecchi

Publications and source records attributed to G P Vecchi.

At least 19 recordsLinked to original sources
PubMed1991

[Computerized graphic techniques in the interdisciplinary information communication in geriatrics].

Geriatric research shows that multidimensional assessment (MA) is the best method of approaching the complex functional problems of elderly subjects which are characterized by a close interdependence of clinical, social and mental factors. A correct and standardized communication of the results and the indications deriving from this complex interdisciplinary system is essential to enable the operators, despite their different professional backgrounds, to become involved in ensuring the health and welfare of their patients using integration and coordination criteria which are appropriate to the patient's individual situation. In this context, a computerized MA programme, known as "Senior", has been designed. The programme provides two communication sheets of data with different professional orientations: I) geriatric assessment sheet for doctors and other medical staff; II) graphic geriatric assessment sheet for non-medical operators. In practice, these assessment sheets are a useful backup in providing continuity between in- and out-patient programmes.

Aged↗
PubMed1990

Methodology of a controlled clinical study for cerebral aging evaluation.

A multicentre study was planned and executed to evaluate the effect of acetyl-L-carnitine in the treatment of cerebral aging. Using 42 health centres, whose comparability of methodology was ensured through a training seminar and an instructional booklet on the psychometric battery of tests employed, some 400 elderly patients aged 60-80 years were enrolled using strict selection criteria. Treatment was run in four phases over 150 days. The first phase, serving as the baseline evaluation, defined through a battery of tests, consisted of 30-day placebo treatment. In the second phase of 45 days, daily treatment with 1500 mg acetyl-L-carnitine was given followed by a psychometric evaluation. For the next 45 days the same drug therapy was employed with a complete psychometric evaluation on the final day. In the last phase of 30 days the placebo was again administered and a final assessment made of the residual benefits of the 90-day treatment with acetyl-L-carnitine. Using this plan made it possible to evaluate the placebo effects, perform cross-study comparisons and demonstrate the effectiveness of the drug treatment.

Acetylcarnitine↗
PubMed1987

[Evaluation of pharmacologic treatment associated with motor-activation therapy in the prevention of senile impairment].

The study was designed to assess any changes in certain aspects of aging produced by combined drug (buflomedil) and motor activation therapy (MAT). The study was conducted on 3 selected groups of 10 women aged 60-74 years with initial signs of mental and physical senile impairment as revealed by appropriate psychometric and laboratories tests. The 3 groups (I: control, II: MAT, III: buflomedil + MAT) were given a series of cognitive, behavioural, affective and cardiovascular tests before and after the 6-month study. The results showed a deterioration in the parameters considered among the control group and a significant improvement especially in cardiovascular, affective and behavioural parameters as well as certain cognitive aspects (attention, mental state) in the group treated with MAT only. The combination of MAT and buflomedil had a positive influence on all parameters considered. In particular it acted extensively on the cognitive parameters. It is therefore concluded that the combination of MAT and drug treatment is a valid system for the prevention of senile impairment since it acts on the main biological, psychological and social aspects of the elderly patient.

Aged↗
PubMed1985

Pain measurements in right-left cerebral lesions.

Left- and right-brain damaged (BD) subjects were examined to ascertain whether psychophysical parameters of pain-pain threshold (P), tolerance threshold (T), and pain endurance (E)-were modified by brain damage and whether differences exist between LBD and RBD. Noxious stimulus was provided by electrical stimulation. Results showed that P and T scores for the paralysed arms were consistently higher than those of the contralateral side. This was not simply due to modified sensitivity alone; in the RBD group hemi-inattention and aphasia in the LBD group also played a role. A significantly hightened value of pain endurance was found only in the healthy arm in the RBD group.

Aged↗