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Biomedical subjects

G Pageaut

Publications and source records attributed to G Pageaut.

At least 19 recordsLinked to original sources
PubMed1990

[Cervical chordoma. Apropos of a case].

The chordomas are malignant tumors arising from the remnants of the posterior spinal chord. The chordomas of the cervical spine are rare (5% of the spinal chordomas). A new case of spine chordoma at C5 level in a 76 years old woman is reported. The diagnosis depends on the results of the histological studies and especially the studies of the labelled elements as Protein S100 or Cytokeratin. Firstly a double osteosynthesis was realized by an anterior and posterior approach. There was no radiotherapy after this operation. A new operation for a fracture of odontoid process was necessary one year later. There was no recurrence. The patient was complaining from pains, two years after the first operation in relation to lateral recurrence. A third operation by an anterior approach was realized. A radiotherapy of 50 Gy was applied on the same level. The first osteosynthesis was with acrylic cement and the second one with an autologous bone graft and a plate after removing the cement without problem. Actually she is in good health, 78 years old.

Aged↗
PubMed1989

[Spinocellular epithelioma of the hand. Apropos of a diffuse and extensive commissural form].

The authors report a case of squamous cell carcinoma of the hand unusual because of its very rapid extension: A 64 year old man was referred to us for treatment of a keratoacanthoma located in the thumb web (histological diagnosis on two occasions). In fact, the histological frozen-section examination at the time of surgery revealed a well differentiated squamous cell carcinoma. A wide excision of the tumor was carried out together with amputation of the index finger according to Chase's technique. Axillary lymphadenectomy was performed due to clinical evidence of regional lymphatic spread (large node) twenty one days following surgery. Four months later, a recurrence in the thumb web required radiocarpal disarticulation. Three months later, a new recurrence at the stump, spreading to the forearm, necessitated an above-elbow amputation. In relation to this unusual case, the authors emphasize the importance of initial diagnosis and the difficulties of surgical management of this tumor, especially in palmar and web or deep locations.

Amputation, Surgical↗
PubMed1988

Degenerative spondylolisthesis, synovial cyst of the zygapophyseal joints, and sciatic syndrome: report of two cases and review of the literature.

Two cases of sciatica secondary to nerve root compression by a "synovial cyst" of a zygapophyseal joint are described. In light of these 2 cases and on reviewing the literature, it appears that zygapophyseal joint osteoarthritis with degenerative (or articular) spondylolisthesis can be a predisposing factor to the formation of such synovial expansions and, consequently, the cause of nerve root compression. The coexistence of a lumbar degenerative spondylolisthesis with a radicular syndrome should therefore encourage early investigation by computed tomography scan, so that conservative treatment would not be unnecessarily prolonged.

Adult↗
PubMed1987

[Primary cerebral lymphoma. Diagnostic and therapeutic values. Apropos of 4 cases].

The authors report four recent cases, of primary cerebral Lymphoma discovered since the use of the C.T. scan. Even though rare, the incidence of this tumor seems to be in slowly increase. The lesions on the C.T. scan are too variables and the surgical biopsy is necessary for the diagnosis. The primary cerebral Lymphoma should be considered more and more like the others Lymphomas. For this reason, they have started the treatment after surgical biopsy, with chemotherapy followed by radiotherapy associated with corticotherapy. The two last patients, are still alive with a follow up of 36 months for one of them. The prognosis seems to us, better as much as the diagnosis and the treatment was started early.

Adult↗
PubMed1986

[Subungual glomus tumor. A case of unusual form].

The authors report a case of glomus tumour developing beneath the nail of the ring finger in a 95 year old woman. In contrast with other similar cases, the pain was moderate and had been present for 20 years. The bony phalanx was deformed. Microscopic examination confirmed the diagnosis of a glomus tumour developing in the soft tissues. The phalanx was amputated.

Aged↗
PubMed1986

[Recurrence of hyperparathyroidism following a parathyroid autograft. Hyperplasia or carcinoma?].

The authors report a case in which hyperparathyroidism recurred after total parathyroidectomy and autogenous parathyroid graft into the fore-arm musculature, in a patient with chronic renal failure. Light and electron microscopic studies of the grafted tissue show a severe, nodular hyperplasia. This case report illustrates the rapid "tumour-like" growth of the hyperplastic parathyroid grafted tissue; according to some authors, the hyperplastic parathyroid tissue displays an increased propensity to become malignant.

Adult↗
PubMed1985

Lipoma in the cerebellopontine angle.

A case of lipoma in the cerebellopontine angle is reported. Intracranial lipomas are very rare, especially in the cerebellopontine angle. To our knowledge, only four cases, including our own, have been operated upon. Until now, total extirpation has not been possible. The singular appearance on computed tomography scanning of this dysembryoplasia is presented together with a bibliography of this subject.

Adult↗
PubMed1984

[Daily rectal bleeding caused by venous angiodysplasia of the rectum].

The authors report a case of venous angiodysplasia of the rectum in a child. This 5 years old boy presented rectal bleeding about each day. The treatment was abdomino-anal pull through resection of the rectum. The localisation of this malformation is quite exceptional in the literature.

Child, Preschool↗
PubMed1983

[Latent pituitary adenoma. Autopsy study].

The incidence of latent pituitary microadenoma is poorly known as few studies have as yet been carried out. To address this problem, microadenoma was systematically looked for during 100 random routine post-mortem examinations in subjects with no endocrine disorders. Microadenoma was found in ten cases. Immunocytochemical study demonstrated prolactinoma in 6 cases, somatotropic adenoma in 1, mixed adenoma in 1, and non-functional adenoma in 2. Microadenoma seems more prevalent between fifty and sixty years of age. Outcome is discussed: spontaneous resolution, growth with onset of clinical manifestations, or persistence without changes in size.

Adenoma↗
PubMed1982

[Deposits of unusual structure in lupus glomerulonephritis].

The authors report a case of Lupus nephritis shown by ultrastructural analysis of subendothelial, mesangial and especially subepithelial deposits formed by aggregates of electron-dense straight tubular structures 20 to 30 nm in diameter. These unusual structural deposits, always identical, are observed in 4 biopsies performed over 8 years during the management of Systemic Lupus Erythematosus in a young woman. They are compared to the usual "Fingerprint" deposits of Systemic Lupus Erythematosus and to the geometric type deposits of cryoglobulinemic glomerulonephritis.

Adult↗
PubMed1979

[Achondrogenesis. Apropos of a case].

The authors report a new case of achondrogenesis, the study of which is principally directed towards the histopathological examination of the conjugal cartilage. A brief review of the literature recalls the main clinical, radiological and histopathological characteristics of this fatal chondrodysplasia transmitted by an autosomal recessive means. In addition to other features, it reveals the difficulty which may be experienced in differentiating between the two types (I and II). Finally, the differential diagnosis is briefly assessed, the problem being the elimination of other non-transmissible chondrodysplasias, in particular thanatophoric dwarfism, for the purpose of appropriate genetic counselling.

Bone Diseases, Developmental↗
PubMed1978

[Rectoscopy: a useful tool to diagnose pseudomembranous colitis (author's transl)].

The authors have performed nine rectoscopies in 14 cases of pseudomembranous colitis. A rectoscopic appearance enables eight times out of nine to diagnose the disease, which asserts itself in all cases by biopsies. Out of the nine cases, two had previously undergone an unnecessary laparotomy, and for three cases the diagnosis of rectal tumour established on rectal digital examination is twice set right by rectoscopic appearance and three times by biopsies. In the remaining five cases with mild intestinal symptoms and severe associated disease the diagnosis was only made with autopsies. A systematic rectoscopy with biopsies is indicated in all patients treated with antibiotics who present an unexplained diarrhea, collapsus or acute abdominal syndrom.

Adult↗
PubMed1978

[Bronchopulmonary "tumouriet" Rare aetiology of an isolated rounded opacity (author's transl)].

In the case described, the onset of haemoptysis led to the discovery of a rounded opacity at the left base. All investigations being negative, thoracotomy was performed. The diagnosis could then be made by histology. Bronchopulmonary "tumourlets" are rarely seen (184 cases) masses of epithelial cells which are usually discovered by chance within areas of altered pulmonary tissue. Forms with clinical or radiological manifestations are extremely rare, only 4 other cases having been described. The pathogenesis of these tumours has been the object of recent ultrastructural studies which have shown the relationship which exists between "tumourlet" and carcinoid tumour. It would thus seem reasonable to classify "tumourlets" amongst the tumours of the diffuse endocrine system. The authors nevertheless feel that it would be premature to name them as bronchial carcinoids of tumourlet type. The concept of "tumourlet" as a separate entity should be retained.

Aged↗