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Biomedical subjects

G Pardo

Publications and source records attributed to G Pardo.

9 recordsLinked to original sources

Morphometry and classification of the cat hypothalamic capillaries using multivariate analysis.

Multivariate statistical methods were used to do morphological determination of the amount and the relation of the astrocytic foot processes (AF), astrocytic lamina (AL) and dense zones (DZ) on hypothalamic capillaries. We corroborated that 100% of the perivascular membrane is surrounded by glial astrocytic cytoplasm. Principal component analysis shows that the original variables are independent of one another. Cluster analysis confirms the individual situation obtained through the principal component analysis. Discriminant analysis shows that the discriminant capacity of the 3 variables is very significant. For the potential interrelations of astrocytic foot processes, astrocytic lamina and dense zones we have clearly differentiated four groups of hypothalamic capillaries.

Animals

How accurate is ultrasonography in monitoring IUD placement?

The insertion of two different types of intrauterine devices (Multiload 250 and Silver T) has been monitored in 97 patients through systematic exploration by echography and hysteroscopy. Both techniques seem to be highly reliable in spite of the observation of 9% misplacements of the IUDs not detected by echography. In addition, hysteroscopy enables the diagnosis of frequent associated pathology (endometrial hyperplasia, endometriosis, polyps) difficult to diagnose by echography. The present study demonstrates the fact that the ultrasonography confirmation of IUD localization in the uterus was not always accurate.

Female

Abdominal ultrasonography versus transvaginal scanning: accuracy in follicular development evaluation and prediction for oocyte retrieval in stimulated cycles.

Abdominal and vaginal sonographic monitoring were compared in 45 patients undergoing follicular development for the purposes of artificial insemination (N = 22) and in vitro fertilization (IVF; N = 23). Transvaginal sonography recorded a significantly (p less than 0.05) higher number of follicles from cycle day 10 on, compared to the abdominal (sector and linear) approach. Starting on day 8, the size of the dominant follicle was also significantly (p less than 0.05) higher when transvaginal endosonography was used. The number of follicles greater than 15 mm on the day of human chorionic gonadotropin (hCG) administration was correlated with the number of oocytes retrieved in patients undergoing IVF. There was a significant linear correlation when transvaginal (r = 0.86, p less than 0.001) and sector (r = 0.57, p less than 0.05) scans were used.

Female

[Vaginal endosonography in extrauterine pregnancy].

The real value of vaginal sonography in the early diagnosis of ectopic pregnancy was assessed in 12 cases where ectopic pregnancy was suspected by clinical evolution and levels of B-HCG, and subsequently confirmed by microlaparotomy. The results were compared with those obtained with abdominal sonography and values of B-HCG. Vaginal sonography gave no false negatives and the percentage of false positives was 16.6%. The most typical echographyc images were: 1. Adnexal Mass (50%), 2. Pseudoring (42%), 3. Yolk sac &/or Embryo &/or Heart rate (25%). Values of B-HCG greater than 600 mIU/IS without embryo from 35th day are highly suspicious with regard to ectopic pregnancy.

Adult

[Sonographic diagnosis of holoacardius].

In the 28th week of gestation a normal foetus and a holoacardius were diagnosed via sonography in a biamnotic monochoriatic twin pregnancy. The growth of the foetuses was observed under continuous sonographic control up to the 40th week of pregnancy. The patient delivered a healthy twin by Caesarean section and the acardius was subjected to a postmortem. Macroscopic and histological findings in the foetus, the placenta and the umbilical cords are demonstrated. The pathogenesis of the holoacardius is discussed as being due to chromosomal aberrations and foeto-foetal transfusion syndrome.

Abnormalities, Multiple

Granular cell myoblastoma (GCM): contribution of three cases with genital involvement.

Granular cell myoblastoma (MGC) is an uncommon benign tumor of mesodermal origin of which no more than sixty cases with genital involvement have been reported. Among the genital organs, the labium majus of the vulva are the predilect site. We hereby contribute three new cases with a genital location (two in the vulva and one in the breast) and review the literature on the subject.

Adolescent

Ontogenetic development of pancreatic thyrotropin-releasing hormone in human foetuses and in infants.

The ontogeny of thyrotropin-releasing hormone (TRH) in pancreata of human foetuses from 15-36 weeks of gestation and of infants has been studied. TRH was detectable in the pancreas of a 15 week old foetus; a progressive increase of pancreatic TRH content was observed until the 34th week of gestation, whereas a progressive decrease was found in the late period of pregnancy and in 1 year old infants. In contrast, the pancreatic insulin content showed a progressive increase during the entire pregnancy and in the first year after birth. These data indicate that TRH and insulin have different ontogenetic patterns in the human pancreas.

Female