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Biomedical subjects

G Pascalis

Publications and source records attributed to G Pascalis.

At least 19 recordsLinked to original sources
PubMed1987

[Staff-patient meetings at the psychiatric unit of a university hospital center].

Staff/patients meetings have been held for 10 years within a mental teaching hospital for adults. The meeting was initiated by a clinical psychologist still in charge of it. The patients have developed the following themes: (i) entrance conditions, (ii) everyday life information, (iii) inconveniences, (iv) mental illness, (v) the exclusion process. The least severely affected patients will exclude the other ones on ground of insanity. Yet all patients consider themselves banned from society, and even feel rejected by the stall at times. The meeting is meant as a regular talk scène. Individual or collective conflicts arising between the patients can be settled there. Patient passivity may also be counteracted. Staff seminar should work up clearly the data provided by the meeting.

France↗
PubMed1986

[Plasma levels of clomipramine and declomipramine in patients with depression: a study of its correlation with therapeutic efficacy].

Twenty four in-patients with an endogenous or non endogenous depressive syndrome (9 and 15, respectively) were treated in hospital for 21 days with various dosages regimens of clomipramine. Plasma concentrations of clomipramine and demethylclomipramine were determined once a week in blood samples. Therapeutic effects were assessed with Hamilton Rating Scale. At day 21, optimal therapeutic effect was observed when the sum of clomipramine and demethylclomipramine plasma levels was situated between 200-400 ng/ml.

Adolescent↗
PubMed1983

[The Lewis blood group is more frequently nonexpressed in psychiatry than in the general population].

The Lewis-negative blood group seems to occur more frequently in psychiatry than in the overall population. The Lewis group is not genetically determined at birth as Lewis-positive or negative; the latter occurs significantly more often among 219 "overall" psychiatric patients than in the overall population: 47% instead of 10%. As a first approximation, the absence of transition from its negativity to positivity seems to constitute a favoring factor for the subsequent clinical development of a psychiatric syndrome, without allowing to predict its nature or severity. For the other blood groups, the genetic determination of which is irreversible, the same sample shows the same repartition as in the overall population.

Adult↗
PubMed1980

[136 karyotypes in psychiatry: surprising results].

136 patients admitted into a psychiatric unit underwent a routine caryotype examination, without any previous selection, 9 anomalies were noticed, including one case of X-tetrasomia, reported elsewhere, and eight mosaics. The patients concerned do not present any morphological anomaly or intellectual deficiency. The authors consider those--mostly gonosomial--mosaics as a minimal brain damage, favourising the appearance of the particular psychiatric syndrome.

Adolescent↗
PubMed1977

[Manic-depressive psychoses. Chronic treatment with tricyclic antidepressive agents].

Long-course Tricyclic anti-depressing treatment affonds clinical healing--i.e. abolition of the recurrences--in melancolic unipolary periodic depressions. This treatment--T.A.T.C.--allows a good prevention of melancolic recurrences in bipolar periodic patterns of psychosis. For the authors Lithium and/or Dipropylacétamide are not sufficient protection for melancolic or maniac recurrences in this patterns. It seems to be three patterns in fact: pure melancolic, pure maniac, and maniaco-depressive. Therapeutic and psychopathologic considerations.

Adult↗