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Biomedical subjects

G Passerini

Publications and source records attributed to G Passerini.

12 recordsLinked to original sources
PubMed1990

Low-dose dopamine during cardiopulmonary bypass in patients with renal dysfunction.

Thirty-six patients with preoperative renal dysfunction were studied to evaluate the effects of dopamine (D) and dopamine-nitroprusside (DN) on renal function during cardiopulmonary bypass (CPB). No differences from the control group (C) were found in creatinine clearance, fractional sodium excretion, osmolarity and free-water clearance. Sodium output/intake ratio during CPB was higher in group D than in groups C and DN (P less than 0.05); water output/intake ratio was higher in group D than in group C (P less than 0.05). Urine lysozime levels and alpha-glycosidase/creatinine ratios increased similarly in the three groups, suggesting ischemic tubular cell damage. No patients showed acute postoperative renal failure or a worsening of their renal dysfunction. The data suggest an increased water and sodium excretion during CPB with a dopamine infusion, possibly resulting from a renal vasodilator effect that was abolished by simultaneous nitroprusside administration.

Aged↗
PubMed1990

Vescica Ileale Padovana: a technique for total bladder replacement.

A new technique for detubularized and originally reshaped ileal total bladder replacement following radical cystectomy for bladder cancer is described and named 'Vescica Ileale Padovana'. 16 patients have been clinically, radiologically and urodynamically evaluated with a follow-up ranging from 4 to 18 months (mean 10 months). The complication rate was low: 1 ureteroileal stenosis; 2 urethroileal strictures. Daytime continence was perfect in 87% (14 of 16 patients). Nighttime continence was perfect (dry sleep for 6-7 h) in 81% (13 of 16 patients). The reservoir features were: high capacity (400-650 ml); low pressure (mean pressure at capacity 17 cm H2O no pressure waves in 50% of patients 30-50 cm H2O wide pressure waves with 250-ml threshold volume in 50%); absence of reflux; complete voiding by abdominal straining, and perineal relaxation.

Cystectomy↗
PubMed1988

The morphological basis of ureteral peristalsis. An ultrastructural study of the rat ureter.

The ultrastructure of the normal rat ureter has been studied in order to correlate the morphological findings with the function of the organ. Electron microscopy demonstrates that the ureteral musculature behaves as a functional syncytium which permits the spread of electrical excitation from cell to cell. A scanty number of nerve endings without evidence of autonomic ganglia was found throughout the ureteral layers. These morphological data support the hypothesis that ureteral peristalsis is an essentially myogenic phenomenon, the influence of the autonomic nerve supply being limited to modulating peristalsis and influencing ureteral tonus.

Animals↗
PubMed1985

Role of the diuresis renogram in the study of the pelviureteric junction.

A consecutive series of 29 patients (33 pelviureteric units) with urographic signs of altered passage through the pelviureteric junction underwent diuresis renography performed by means of an intravenous injection of 99mTc-diethylenetriamine pentaacetic acid/kg body weight followed by intravenous administration of frusemide. Anderson-Hynes pyeloplasty was performed in 19 pelviureteric units with a modest or almost absent fall in the renographic curve after diuretic injection; 2 other symptomatic patients, in whom a moderate fall of the same curve was found also underwent surgery. Complete normalization of the renogram was observed in 17 of 21 operated patients. Severe functional deficit and polymegacalicosis were evident in 3 and 1 patient, respectively, with unchanged postoperative renograms. During follow-up (6 months to 2 years) diuresis renography remained unaltered in non-operated units. Our experience indicates how the diuresis renogram not only gives functional confirmation of a pelviureteric junction obstruction, but is also helpful in resolving situations in which there is a discrepancy between symptoms and urographic signs. Furthermore it provides an accurate method for evaluating the results of pyeloplasty. However, the use of this investigation is not, in our opinion, indicated in the presence of severe functional deficit of the kidney or pyelectasis.

Adolescent↗
PubMed1977

The elastic tissue of the adult dilated ureter.

Adult dilated ureters have been examined in order to calculate the amount of the elastic tissue. From the histological observations and by the chemical analyses performed on the extracted elastin a decrease of the elastic tissue, as compared to the normal adult ureters has been noted. In fact, in the adult normal ureters, the elastin accounts for 9% of the dry matter, while in the abnormal the elastin represents 6.5%.

Adult↗
PubMed1977

Primary obstructed megaureter.

The clinical presentation and management of 57 primary obstructed megaureters in 46 patients, 35 of whom were children, are reported. Indications for operation include pain, infection, progressive pyelo-ureteric dilatation and reduction in the glomerular filtration rate. We have found that affected children cannot be managed successfully without operation. Conservative treatment may be employed effectively in adults in whom the condition is often stable and complications are less frequent. The preferred surgical technique is ureteric narrowing with reimplantation to the bladder by the Politano-Leadbetter method. The results of surgery are less satisfactory in adults than in children. This may be related to the reduced quantity of elastic tissue in the ureteric wall in adult cases.

Adult↗
PubMed1976

The elastic component of normal and dilated ureters in children: chemical and histochemical characterisation.

Using chemical and histochemical techniques, it has been possible to calculate the exact amount and distribution of the elastin in normal and abnormal ureters in children. From the quantitative analyses, it has been calculated that in the dilated ureters the elastin content represents the 3% to 5% of the organic material, while in the normal ureters it is less than 1%.

Amino Acids↗
PubMed1976

Ureteric substitution with a tapered ileal loop. An experimental study.

The authors present their experience in replacement of the ureter by a tapered ileal loop over a 24-month period, in a group of 10 dogs. With regard to the morphological and functional behaviour of the neo-ureter, the results on the whole were considered satisfactory. However, some problems such as pyelonephritis, associated with obstruction due to mucosal hyperexcretion, remain unsolved at the present time.

Animals↗