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Biomedical subjects

G Peer

Publications and source records attributed to G Peer.

67 records · Page 4Linked to original sources
PubMed1984

Long-term treatment of arterial hypertension with verapamil.

Based on the vasodilator properties of calcium antagonists, verapamil was recently introduced into the treatment of arterial hypertension. The present study was undertaken to examine the long-term efficacy of this drug in mild and moderate hypertension. In 82 patients with uncontrolled primary or renal hypertension, verapamil was used either alone or in combination with other drugs. In six cases verapamil was withdrawn because of side effects. In the remaining patients a normal average blood pressure was achieved within 7.8 +/- 1.2 weeks of treatment with doses not exceeding 400 mg/day. This effect was maintained for up to 4 years of treatment, although tolerance seemed to develop in about 10% of the patients. In view of this good response and minimal side effects, it is concluded that verapamil is an effective addition to the antihypertensive arsenal.

Adult↗
PubMed1983

Low blood pressure in vegetarians: the possible role of potassium.

Ninety-eight confirmed adult vegetarians were examined against a matched group of nonvegetarians living in the same urban environment in order to evaluate the prevalence of arterial hypertension. The average blood pressure was 126/77 for the vegetarians and 147/88 for the control group (p less than 0.05). Significantly lower blood pressure was found in every decade of age. Only 2% of the vegetarians had hypertension (higher than 160/95) as compared to 26% hypertensives in the nonvegetarians. These differences in blood pressure were maintained also when individuals with the same "relative weight" were compared. Family history of hypertension was similar in both groups. Analysis of factors such as coffee drinking and smoking did not favor reduced blood pressure among the vegetarian group. Sodium and potassium intake were evaluated from their ratios to creatinine in a single urine sample. It was evident that both groups excreted the same amounts of sodium, while potassium excretion was significantly higher in the vegetarians. In view of the increasing evidence that potassium plays an important role in the regulation of blood pressure it is concluded that the protective antihypertensive factor in the vegetarian diet is the presence of high amounts of potassium.

Adult↗
PubMed1982

Dialysis-induced eosinophilia.

Blood eosinophils were counted by the counting-chamber method in 21 regular hemodialysis patients. Before dialysis, eosinophil counts were within the normal range in all patients (mean 98 cells/mm3, range 6-350). After the first 15 min of hemodialysis, with not reused coils or hollow-fiber dialysers, a significant drop in eosinophil counts was noted in all patients. The mean drop was 37.5% of the initial value (range 28-100%). At the end of the 5-hour dialysis, the eosinophil counts rose significantly in all patients but 1. The mean rise was 521% of the initial counts (range 22.3-1576%). Simultaneous neutrophil counts showed the already described drop at 15 min with a return to predialysis levels at 5 h. Predialysis IgE serum concentrations were lower than normal (mean 24.8, range 4.5-58 units/ml), and did not change at the end of the dialysis. It seems that pulmonary sequestration is responsible for both neutropenia and eosinopenia early in dialysis. The marked eosinophilia at 5 h may be the result of a release of eosinophilotactic substances induced by the dialysis procedure itself.

Adult↗
PubMedDate not supplied

The management of an early-missed abortion after radical trachelectomy--a case report and a review of the literature.

UNLABELLED: Radical trachelectomy (RT) has been reported for almost 20 years. This case report describes and addresses the issue of the clinical management of early-missed abortion in a patient after RT with a cerclage. CASE: A 35-year-old woman who had a RT 2 years ago due to cervical carcinoma stage IB1 presented with a missed abortion of an 8-week gestational age. At the end of the RT, a cerclage suture was inserted in the remaining internal oss of the cervix. The patient went through a cervical dilatation followed by suction curettage guided by ultrasonography without compromising the cerclage. This case report suggests that dilatation and suction curettage without compromising the cervical cerclage is a feasible option in the clinical management of early abortion in a patient after RT.

Abortion, Missed↗