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G Phillipou

Publications and source records attributed to G Phillipou.

66 records · Page 4Linked to original sources

The quantitation of plasma phytanic acid by mass fragmentography.

Plasma phytanic acid has been quantitated by mass fragmentography after its successive reduction and derivatization to the corresponding t-butyldimethylsilyl ether. The latter was estimated by selective ion monitoring of its characteristic (M-57) ion (M/z 355). The technique has the advantage of being more rapid, specific and sensitive than existing methods, permitting the determination of phytanic acid at levels greater than 5 mug/ml plasma.

Chromatography, Gas↗

Computer based quality assessment of hospital capillary blood glucose monitoring.

A quality control (QC) programme to continually monitor the reliability of hospital ward capillary blood glucose levels has been developed based on a memory blood glucose meter interfaced to a portable microcomputer. Over a 38-week period some 12,500 ward QC tests were performed by approximately 200 accredited operators. Although the mean weekly coefficients of variation were all less than 15%, there was a marked variation between wards, with the frequency of testing of patients the major factor influencing reliability. However an external laboratory-based QC programme suggested a high degree of proficiency which was not achieved by any ward on internal QC assessment.

Blood Glucose↗

The 1-h 50-g glucose challenge does not predict large-for-gestational-age infants.

The relationship between the 1-h 50-g glucose challenge performed at 24-28 weeks and subsequent birth of a large-for-gestational-age infant was examined in a cohort of 368 Europid women who had no pre-existing medical condition and experienced no pregnancy complications. The results established that the 1-h 50-g glucose challenge blood glucose level had no predictive power with respect to the birth of a large-for-gestational-age infant. However, the 1-h blood glucose value was found to be significantly related to maternal height, weight and age, indicating that its level also represents processes unconnected to glucose intolerance. The study findings also re-confirmed the importance of parity, height, sex, and weight as determinants of large-for-gestational-age infants.

Birth Weight↗