[Gonococcal infections; study of the western region comprising 2 surveys].
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Biomedical subjects
Publications and source records attributed to G Pinon.
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Susceptibility of 121 isolates of coagulase-negative staphylococci to two antimicrobial agents, novobiocin and fosfomycin, was determined using the agar dilution method. Isolates included 45 strains of Staphylococcus saprophyticus, 26 strains of S. cohnii and S. xylosus, 24 strains of S. epidermidis and 26 strains of S. hominis, S. capitis, S. warneri and S. auricularis . The minimal inhibitory concentration average of fosfomycin for S. saprophyticus differed (p less than 0.001) from that other for novobiocin-resistant staphylococci (S. cohnii and S. xylosus) and for S. epidermidis (p less than 0.001). Out of 45 isolates of S. saprophyticus, 42 were resistant to fosfomycin. The results were very heterogeneous with regard to fosfomycin for all of the other coagulase-negative staphylococci. Resistance to fosfomycin, like resistance to novobiocin, could be used as a presumptive test for the identification of S. saprophyticus.
A total of 129 strains of Haemophilus influenzae were tested for susceptibility to twelve antibiotics. Capsular serotypes and biotypes were determined, and the relation between these parameters and minimal inhibitory concentrations (MIC) were analysed. Non-capsulated strains were more susceptible to streptomycin than capsulated ones. The distribution of MIC of chloramphenicol among biotypes was different. The distribution of MIC of penicillin G, tetracycline and chloramphenicol among sources of isolation was also different. Therefore the strains did not have the same origin, and one should look at the concept of organotropism for H. influenzae.
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