Biomedical subjects

G Prüll

Publications and source records attributed to G Prüll.

12 recordsLinked to original sources

PubMed1976

[The clinical picture, motor activity, electro-encephalographic, neurophysiologic and linguistic findings in a case of left-sided hemispherectomy (author's transl)].

In a patient aged 35 the left cerebral hemisphere was surgically removed for a cerebral angioma. Cerebral function has been examined clinically and from neurophysiologic, neuropsychologic and linguistic aspects. History, pre-and postoperative clinical findings are described. Post-operative motor-activity was registered continuously with 6 electromyograms. It is described, compared with a case of right sided hemispherectomy and discussed. On the basis of a survey of the literature the cerebral activity before and after operation, examined with quantitative EEG analysis, is described and discussed. After a general exposition of the linguistic ability of the right non-dominant hemisphere it is shown that this must have been a case of left dominance. On this assumption the formal-quantitative linguistic findings after left-sided hemispherectomy are described. The neuro-psychologic tests, pre- and post-operatively carried out with several techniques (LPS, HAWIE, FLT, Token-Test), are compared with each other and the results of further tests (a short form of the "Minnesota-test and our own collection of aphasia tests) after hemispherectomy added. After a survey of relevant descriptions in the literature the postoperative linguistic findings (lexic and morphology, syntax, relationship between idea and expressive realization) are described and compared with similar findings in the literature.

Adult↗

PubMed1976

[The EEG in intensive care units for diagnosis, monitoring and prognosis (author's transl)].

The clinical electroencephalography of the sixth and seventh decade of this century saw its task in the coordination of EEG-findings and nosological entities. The method seemed to be limited to the discovery of positive correlations of EEG-patterns and diagnoses. The psychopharmacological induced psychodynamics of psychoses, the EEG-dynamics of epileptic patients--enforced by anticonvulsant drugs--and the modern intensive medicine teach us nowaday to leave static EEG-reflection and instead turn to a more pathophysiological way of thinking. Clinical EEG deals only with an actual sample of a continuum, a functional diagram of age, brain metabolism, vigilance and a possibly convulsive capacity. The comparison of samples enables us to have a better insight into the gradient of steppness of EEG-pattern changes. It is to be correlated with clinical and biochemical parameters. Further comparison of samples allows criterions concerning the extent of cerebral lesion, its course, termination, with or without neurological deficiency. In a series of cases of acute neurological, neuropsychiatric and internal diseases the above mentioned necessity of a more pathophysiological EEG-interpretation is being demonstrated.

Aged↗

PubMed1976

[Electroencephalographic study of brain-infarction in dogs (author's transl)].

The evaluation of EEG-findings during the acute phase of stroke-patients is somewhat difficult particularly in regard to the voltage-production, less in regard to the temporary retardation of frequency. Within comparable neurophysiological and biochemical examinations of the experimental brain-infarct under standardized conditions of silicon-rubber-embolus was introduced intracarotideally and an occlusion of the media-trunk evoked. One day prior to the embolisation and on the first, third and fifth day thereafter EEG-derivation took place which were stored on analogous-tape, digitalized and were then confronted with the FFT-Algorithm. From the statistical point of view four animal groups were the result: HO-group (control group), H1-, H3- and H5-group (each time N = 6). Visual evaluation of the curves, descriptive and inferential statistics of the spectral EEG estimators showed a significant loss of power within five days after the infarction; it always was more distinct across the focal side than across the not immediately involved hemisphere. On the fifth day the original level of voltage was almost reached again. From the clinical standpoint the neurological deficits had practically been disappeared. The biochemical finishing of the dog-brains -- the results of which are planned to be confronted with the electrophysiological results in another paper -- in accordance with the papers of other authors brings close the assumption that the decrease of tension i.e. the loss of power of the electric potential during the first days after infarction is combined with a temporary decrease of the energetic potential of the metabolically active corticocerebral cells which is tied to the phosphagene-system of the highly energetical phosphates and metabolites of the energy-metabolism in the brain.

Animals↗

PubMed1971