[Decontamination. Treatment of instruments before disinfection or sterilization].
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Biomedical subjects
Publications and source records attributed to G Prost.
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A retrospective study of pleural mesothelioma diagnosed between 1980 and 1988 in the Rhône-Alpes région allowed to identify 224 cases. From the 187 patients in which occupational history was available 105 (56%) had been exposed to asbestos at work and 44 had been recognised as occupation disease and compensated. These data illustrate that the real incidence of the disease is largely underestimated and that legal procedure for occupational disease recognition is highly deficient.
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Azodicarbonamide (Chemical Abstract Service Registry No 123.77.3) is an organic low molecular weight agent used for blowing and foaming plastics. Finely ground azodicarbonamide can be a pulmonary and sometimes a cutaneous acute sensitiser. Four cases of work related asthma are reported.
Occupational asthma can either improve or develop into chronic respiratory insufficiency. It is often difficult to predict which course will be followed. Here we report the follow-up of respiratory function of 23 patients with occupational asthma of at least one year's standing, due to various substances; several prognostic factors are discussed.
Some examples of chemicals and occupational asthmas are summarized. Industrial asthmas are characterized by a large number of risks in relation with a large number of chemicals and uses. Occupational physicians are well informed of risks and work practices in the factories.
The compensation of occupational asthma is based on the presumptive evidence of the cause. This process is both simpler and faster than in case law. In practice however, difficulties can arise, delaying payment of compensation. The main causes of these difficulties and means to overcome them are discussed here.
The compensation of occupational asthma is based on the presumptive evidence of the cause. This process is both simpler and faster than in case law. In practice however, difficulties can arise, delaying payment of compensation. The main causes of these difficulties and means to overcome them are discussed here.
Occupational asthma can either improve or develop into chronic respiratory insufficiency. It is often difficult to predict which course will be followed. Here we report the follow-up of respiratory function of 23 patients with occupational asthma of at least one year's standing, due to various substances; several prognostic factors are discussed.
Some examples of chemicals and occupational asthma are summarized. Industrial asthma are characterized by a large number of risks in relation with a large number of chemicals and uses. Occupational physicians are well informed of risks and work practices in the factories.
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A method for the assessment of diagnosis in human toxicology is presented. This method follows an approach similar to that already used in postmarketing drug surveillance for the validation of drug-induced side effects. It is based on criteria of exposure and semiological/chronological criteria. A scale for objectively assessing these criteria allows one to appreciate the information available in each case report (i.e., informativity), and when this is considered sufficient, the causal relationship (i.e., imputability) can be evaluated. This mode of systematic and objective assessment should allow one to achieve a consistent case-by-case recording of data in occupational as well as human toxicology in general, to stimulate the search for lacking information, to use a common language for all those recording and reporting such data, and, finally, to improve the reliability and usefulness of published reports.
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