[Congenital hypertrophy of the pigment epithelium].
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Biomedical subjects
Publications and source records attributed to G Quentel.
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Ocular fluorophotometry was performed in 24 patients with hypertension due to toxemia of pregnancy and in ten normal subjects. Patients showing features of accelerated hypertension in the fundus (eg, hemorrhage, cotton-wool spots, and disc edema) were excluded from the study. Fluorescein concentrations in the aqueous and posterior vitreous increased significantly in toxemic patients compared with those in normal subjects; the blood-aqueous barrier was disrupted earlier than the blood-retinal barrier. Nevertheless, these barriers were only disrupted when the arterial diameter was altered. Ocular fluorometric abnormalities disappeared after delivery in all but two cases.
Vitreous fluorophotometry was performed on 63 patients undergoing cataract extraction. Pre- and postoperative studies demonstrated that this procedure always induces alterations in the blood-aqueous barrier. A correlation was found between the degree of this alteration and the frequency of cystoid macular edema.
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The film of an angiography by fluorescence presents specific particular characteristics. Treatment of the film has to be adapted to these particularities, and the chemical products used have to be specially chosen. In this way, the results obtained can be greatly improved. The procedure can be automatized by the use of a simple apparatus, and printing on paper causes no particular difficulty.
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The apparition of diabetic retinopathy depends on the duration of the evolution of the diabetes and its control, and its type. The indications for photocoagulation are in progressive retinopathy the existence of macular edema or retinal or prepapillar neovascularisation. The pan-rtinal argon laser photocoagulation is the best technic for treatment. It leads to a global improvement whose results are presented, after 2 years follow-up.
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