Treatment of ventricular tachycardia in an infant.
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Biomedical subjects
Publications and source records attributed to G R Cumming.
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Lead MC5 bipolar exercise ECG was obtained in 510 asymptomatic males, aged 40 to 65, utilizing the bicycle ergometer, with maximal stress in 71% of the subjects. "Ischemic changes" occurred in 61 subjects, the frequency increasing from 4% at age 40 to 45, to 20% at age 50 to 55, to 37% at age 61 to 65. Subjects having an ischemic type ECG change on exercise had more frequent minor resting ECG changes, more resting hypertension, and a greater incidence of high cholesterol values than subjects with a normal ECG response to exercise, but there was no difference in the incidence of obesity, low fitness, or high systolic blood pressure after exercise. Current evidence suggests that asymptomatic male subjects with an abnormal exercise ECG develop clinical coronary heart disease from 2.5 to over 30 times more frequently than those with a normal exercise ECG.
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College girls exercising at home for 19 minutes daily using the 10BX Royal Canadian Air Force exercise plan, with the addition of rope skipping, improved their physical working capacity and maximal oxygen uptake by 7 and 9% after six weeks. No change occurred in a matched control group. Changes in endurance fitness with this type of training are of relatively small magnitude, and reproducible measurements are required for their demonstration. The small gains in aerobic power would seem to be of little practical significance for the subjects, and a major drawback of any home exercise program is the lack of motivation to continue.
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Eight patients with aortic coarctation were studied at rest and during supine bicycle exercise before and after intravenous propranolol 0.17 mg./kg. The mean pressure gradient across the aortic narrowing increased from 16 to 45 mm. Hg during exercise, and was reduced to 11 and 31 mm. Hg after propranolol. Total peripheral resistance was increased by propranolol both at rest and during exercise, and the diminished pressor response was due to a 20 per cent decrease in exercise cardiac output. Brachial artery systolic pressure was reduced more than central aortic systolic pressure in 2 of the 3 patients in whom both pressures were monitored. In one patient descending aortic pressure fell during exercise; in the remainder, slight increases were noted.