A familial aggregate of common variable immunodeficiency, Hodgkin disease and other malignancies in Newfoundland--I. Clinical features.
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Adolescent↗
Biomedical subjects
G R Fraser
Publications and source records attributed to G R Fraser.
A familial aggregate of common variable immunodeficiency, Hodgkin disease and other malignancies in Newfoundland--II. Genealogical analysis and conclusions regarding hereditary determinants.
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Computers↗
Superoxide dismutase variants in Newfoundland--a gene from Scandinavia?
An electrophoretic survey of variant red cell enzyme phenotypes in an isolated community in Newfoundland gave gene frequencies in marked contrast to those found in the capital, St. John's. In particular, a variant of red cell superoxide dismutase (SOD) gave a high variant frequency. Possible origins of the variant SOD allele are discussed.
Alleles↗
[Population genetics].
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Blood Group Antigens↗
Common variable immunodeficiency, Hodgkin's disease, and other malignancies in a Newfoundland family.
A large inbred family is described in which there were seven cases of Hodgkin's disease, three of lymphosarcoma, two of thymoma, two of common variable immunodeficiency, and single cases of retinoblastoma, neuroblastoma, and rhabdomyosarcoma. There have been no other lymphoma cases in the community during the past decade. Further study of this family may help to define the genetic basis for development of Hodgkin's disease and other disorders.
Adult↗