Biomedical subjects
G R Plotkin
Publications and source records attributed to G R Plotkin.
Gastroenteritis: etiology, pathophysiology and clinical manifestations.
The infectious etiologic agents of gastroenteritis are manifold and have only recently been studied in greater depth. Part of the problem in studies pertaining to diarrhea is the difficulty in identifying fecal "pathogens" among an enormous number of indigenous fecal microorganisms. Finally, the recognition of the pathogenicity of enterotoxins has created an awareness of the complexity of gastrointestinal physiology with host-parasite interactions.
Unusual features of Hemophilus infections in adults.
Infections due to species of Hemophilus, especially H influenzae type B, are usually equated with the pediatric age group. However, during the past several years the medical literature has emphasized the occurrence of such infections in adults. Four adult patients are presented who demonstrate certain unique clinical features which have not been recently or previously reported.
Mycoplasma pneumonia presenting as meningoencephalitis and hemolytic anemia.
Simultaneous occurrence of cold agglutinin hemolytic anemia and central nervous system disease due to Mycoplasma pneumonia is extremely rare. A patient is described who initially presented with severe hemolysis and diffuse neurologic dysfunction which appeared during the period of roentgenographic resolution of her pneumonia. Spectrum, pathogenesis, and antimicrobial treatment of the neurologic complications are reviewed.
The bone scan in primary care: diagnostic pitfalls.
Skeletal scintigraphy (bone scanning) is a useful adjunct in the diagnosis of disease states, such as osteomyelitis, and in the evaluation of occult fractures. Certain conditions can alter the appearance of bone scans, such as age of the patient, prior use of antibiotics, concomitant diseases, and disruption of the vascular supply. Three patients whose clinical problems highlight diagnostic problems with bone scans are discussed.