Bad obstetric history: an unusual presenting manifestation of primary hyperparathyroidism.
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Biomedical subjects
Publications and source records attributed to G R Prasad.
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Meticulous staging of ovarian cancer has so far been a prerequisite for treatment planning. However, more than 80% of patients operated by non-oncologists all over the world do not under go a complete staging. Recently there have been reports questioning the need for extensive staging from the point of cervical benefit. We have analysed our data of 64 stage ovarian cancer patients to see if clinical staging was adequate or relaparotomy with restaging is necessary. We conclude that though pathological staging is important for proper reporting of results and evaluation of treatment modalities, in the existing circumstances, a judicious use of clinical methods and taking available pathological factors into account, we can still produce comparable results with restricted use of relaparotomy.
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Thirty-six babies born with an anorectal anomaly were evaluated for vesicoureteric reflux in the neonatal period and the progress of the reflux with age was followed. The overall incidence of reflux was 47%, with higher rates in the more severe types of anomaly. Generally, the reflux was of mild grade and tended to resolve with time, except in the short colon syndrome. Urinary sepsis due to a rectourinary communication may have an important role in the development of reflux.
The prone cross-table lateral radiograph provides equal or sometimes better information, compared to the invertogram, for demonstration of the level of rectal atresia in neonates. Easy positioning, better cooperation of the patient, elimination of the effect of gravity, and better delineation of the rectal gas shadow are the advantages of the prone lateral view. Among the 45 cases compared, equal findings were noted in 37, but in eight babies the level of rectal atresia was more caudal in the prone radiograph than in the invertogram.
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Cisplatinum based chemotherapy has become the standard treatment for ovarian cancers due to its proved superiority over non-cisplat based regimes. However, the therapeutic impact of cisplat based regimes compared to cheaper non-cisplatinum based regimes is questionable when multiple variables such as residual disease, histologic type, grade are introduced. This report is a study of 110 Stage III ovarian cancer patients from 1985-89, with cisplat (n = 69) and non cisplat (n = 41) based chemotherapy. The results of both regimes with reference to the multiple variable factors are presented. We conclude that cisplat based regimes appear to be superior to non-cisplat based regimes except probably in poorly differentiated ovarian tumors where the results were similar with either regimen.