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Biomedical subjects

G R Thurmayr

Publications and source records attributed to G R Thurmayr.

10 recordsLinked to original sources

[Quality management with information systems].

Three information systems are described, whose data are simultaneously used for quality management and others tasks. They show, that the completeness of documented diagnoses is dependent of their appraisal of the physicians. The support of coding by information technology brings an essential improvement. The compliance of physicians with rules has to be reviewed in regular intervals. Quality assurance of a process should be made in short intervals, to be able to intervene in time. Individual efficiency control stimulates each participant to improve his work. These examples show, that information systems can undertake quality management and other tasks besides. Such systems are important, when hospitals attend KTQ-certification.

Documentation↗

[OPS-301/ICPM: experiences and problems].

For over 2 years, the classification of procedures OPS-301 has been uniformly used in all German hospitals. The ICPM in German extension has 5-6 digits and is totally compatible with the OPS-301 restricted to operations. This ICPM is qualified for scientific documentation beyond efficiency control. The OPS-301 needs some better representation and some extensions proposed by medical experts. A program that searches for invalid code numbers and uses the relations of OPS-301 to sex, age, and department in a knowledge base, detects a 10% error rate in manual coding with OPS-301. A coding program reduces them to 1.4%. After mapping the OPS-301 by SNOMED this monohierarchical classification becomes multihierarchical. This is advantageous for coding and retrieval.

Documentation↗

[Quality assurance of GSG data, problems and possible solutions].

Acquisition and controlling of data by our developed knowledge based system extensively substitute human manual controlling of basic data. It is absolutely necessary because it is the only way to prevent expected high error rates and accomplish the lots of data. You have to do it before data transferring to health insurance.

Artificial Intelligence↗

[Labor induction with prostaglandin in post-cesarean section status].

60 pregnant women with previous cesarean section and induction of labour with prostaglandins (PGE2) in the following pregnancy were compared to a collective of 1412 patients with PGE2 induction without any previous uterine surgery, and to a collective of 82 patients with previous cesarean section, but an uncomplicated course of pregnancy and therefore no indication for an induction of labour. Uterine hyperstimulation was more frequent in both collectives with previous cesarean section than in the collective without that risk. In the case of previous cesarean section induction of labour with prostaglandins did not lead to an increased number of uterine ruptures compared to cases with a previous cesarean section. Therefore the induction of labour itself in the case of a previous cesarean section doesn't lead to an increased maternal risk during delivery. Uterine hyperstimulation being rare, the increased number of fetal acidosis and vaginal-operative delivery in the group with previous cesarean section and consecutive PGE2 induction of labour seems to originate rather from the risk which was the indication for labour induction than from the PGE2 application itself. The information of a patient with previous cesarean section and planed induction of labour with PGE2 should therefore put the stress in the necessity of an intensive surveillance during delivery because of the basic risk "previous cesarean section" and the secondary risk resulting from the induction of labour.

Acidosis, Respiratory↗

Computer-aided formulation of physician's reports and storage of ERCP data.

In the 2nd Medical Dept. of the Technical University of Munich, endoscopic retrograde cholangiopancreatography (ERCP) reports are written with the aid of a computer. The doctor doing the examination enters the ERCP data into screen masks. The data are stored at once in a data bank. This data bank system permits immediate error checks of the variables entered, singly and in combination. Errors can be corrected in a loop. Generating of ERCP reports is controlled by a text file, which contains both control statements and standard phrases. A special program for the document generating was developed by the authors and has been used for 15 years in various applications.

Cholangiopancreatography, Endoscopic Retrograde↗

[Pancreatic secretion in domestic sprue].

Pancreatic function was determined (using the secretin-pancreozymin test) before the use of gluten-free diet in 22 patients with endemic (celiac) sprue. Water and bicarbonate secretion were within normal limits, if anything there was a trend to high-normal values. Remarkable and apparently characteristic for celiac sprue was the only slight contraction of the gallbladder after intravenous injection of submaximal doses of cholecystokinin-pancreozymin (CCK). Secretion of the 3 enzymes amylase, lipase and trypsin was decreased in about one third of cases, the difference relating both to the concentrations and the amount secreted, compared with normal control values was significant (P greater than 0.01). But in no case was the reduced enzyme secretion so marked that one would expect maldigestion. Multivariate non-linear discriminance analysis demonstrated that pancreatic secretion in sprue is quite distinct from that in healthy subjects and those with chronic pancreatitis. It is assumed that there is a pattern of exocrine pancreatic secretion typical for sprue.

Adult↗

[Pancreatic secretion of patients with chronic renal insufficiency (author's transl)].

Pancreatic function tests were performed in 15 patients with advanced renal insufficiency. Pancreatic secretion was stimulated with CCK/PZ and secretin and 60 minutes later with bile given intraduodenally and CCK/PZ and secretin intravenously. The Wilcoxon-test showed that there were significantly higher lipase levels in serum and lower amylase amounts in duodenal juice compared to normal volunteers. No differences could be demonstratd for volume, maximal bicarbonate concentration, lipase and trypsin outputs. It could be shown by nonlinear discriminant analysis that pancreatic secretion might specifically be changed in patients with chronic renal failure. These patients can be definitely differentiated according to the secretion pattern from normal controls and patients with chronic pancreatitis, pancreatic carcinoma, chronic and acute duodenal ulcer.

Adult↗