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Biomedical subjects

G Ramanathan

Publications and source records attributed to G Ramanathan.

7 recordsLinked to original sources

Ultrasound examination at 37 weeks' gestation in the prediction of pregnancy outcome: the value of cervical assessment.

OBJECTIVE: To examine the potential value of routine measurement of cervical length in singleton low-risk pregnancies at 37 weeks of gestation in the prediction of onset and outcome of labor. METHODS: Cervical length was measured by transvaginal sonography at 37 weeks in 1571 singleton low-risk pregnancies. Outcome measures were gestation at spontaneous onset of labor, post-term delivery, duration of labor and mode of delivery. RESULTS: The median cervical length at 37 weeks was 30 mm and there was a significant association between cervical length and gestation at delivery, which increased from a mean of 38 weeks for cervical length of 10 mm to 41 weeks for cervical length of 35 mm. The incidence of delivery after 40 weeks and 10 days was 296 (18.8%) and the incidence increased with cervical length at 37 weeks from 0% to 6%, 35% and 68% for respective cervical lengths of < 20, 21-30, 31-40 and 41-50 mm. In the pregnancies with spontaneous onset of labor the incidence of Cesarean section for failure to progress increased from 3.6% to 6.0%, 6.4% and 11.8% for cervical lengths of < 20, 21-30, 31-40 and 41-50 mm, respectively. In the pregnancies requiring induction for post-term the incidence of Cesarean section for failed induction or failure to progress increased from 7.5% to 20.1% to 25.0% for cervical lengths of 21-30, 31-40 and 41-50 mm, respectively. CONCLUSION: Measurement of cervical length at 37 weeks can define the likelihood of spontaneous delivery before 40 weeks and 10 days and the risk of Cesarean section in those requiring induction for prolonged pregnancy.

Adolescent↗

Attention-deficit/hyperactive disorder: making a case for multidisciplinary management.

Attention Deficit/Hyperactivity Disorder (AD/HD) is characterized by a cluster of age-inappropriate behavioral abnormalities comprising inattentivity, hyperactivity and impulsivity. The definition is controversial and without an accurate diagnosis. Therefore, it seems prudent that a multidisciplinary treatment protocol should begin with non-drug psychological and behavioral strategies plus nutritional intervention.

Antidepressive Agents, Tricyclic↗

Dental findings in a patient with biliary atresia.

The dental treatment of a 3-year-old male with biliary atresia is discussed. The patient was scheduled for a liver transplant and was receiving Cyclosporine A. Due to the severity of the dental condition and to reduce the possibility of infection, all twenty primary teeth were extracted. The extracted teeth displayed a marked greenish discoloration of both the crowns and the roots. Histological examination revealed extensive interglobular dentin, a number of faint yellow-brown lines contouring the developmental pattern and a distinctive fluorescent line. The dental and pharmacological considerations relating to the treatment plan for this case are reviewed.

Biliary Atresia↗

Prevention of overbite and overjet development in the 3 to 8 year old by controlled nighttime guidance of incisal eruption: a study of 43 individuals.

The purpose of this study conducted at Tufts University School of Dental Medicine is to investigate the possibility of limiting the development of an excessive vertical overbite and horizontal overjet during sleeping hours in young children prior to and during the eruption of the permanent incisors. A sample of 43 individuals, whose mean age was 6.17 years, wore a Preventive Eruption Guidance Appliance passively only while sleeping at night for 13 months (mean) to control the development of the overbite as the permanent incisors erupted and to correct the excessive overjet. The mean initial overbite of the sample was 3.4 mm and was reduced to 1.4 mm. The mean initial overjet was 3.0 mm and was reduced to 1.4 mm. Fourteen percent (6 cases) of the sample had an open bite of 1.84 mm (mean), which was reduced to a mean open-bite of 0.81 mm. As a result of the statistical comparison between the treatment sample to the control sample of 50 non-treated individuals, it was shown that the reduction of the overbite and overjet was accomplished solely by altering the problematic dentition without affecting the normal growth pattern or facial morphology as measured from nine lineal dimensions. It was also shown that the change in overbite and overjet was a significant improvement over what would have occurred if no intervention had been instituted, and that the overbite was corrected by restricting continued excessive eruption of the maxillary incisors with only nighttime passive use of the appliance.

Child↗