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Biomedical subjects

G Ranner

Publications and source records attributed to G Ranner.

At least 73 records · Page 4Linked to original sources

[Computerized tomography in the diagnosis of allergic bronchopulmonary aspergillosis].

In four patients with immunologic and laboratory findings consistent with allergic bronchopulmonary aspergillosis a CT of the chest was performed. CT revealed central bronchiectasis in all patients. Other features of the condition revealed by CT were mucoid impaction, peripheral alveolar infiltrates, and segmental or subsegmental atelectasis. Owing to their central location the bronchiectatic bronchi always appear parallel to the image plane. This means they can generally be visualized by CT.

Adult↗

[Malignant bone marrow infiltration in nuclear magnetic resonance tomography].

Magnetic resonance imaging (MRI) is currently the only non-invasive method detecting changes of bone marrow. While yellow bone marrow produces a high signal intensity, which is similar to subcutaneous fat, any other cellular infiltration of the bone marrow causes a decrease of signal intensity because of replacement of marrow fat cells. In this report we describe two patients, who underwent MRI because of clinical symptoms of coxitis, in order to exclude Perthes disease. Both cases showed decreased signal intensity of the bone marrow particularly of the proximal femura, highly indicative of cellular bone marrow infiltration. Bone marrow aspiration in these patients showed acute lymphocytic leukemia in one case and marrow infiltration by neuroblastoma cells respectively in the other case. Because of its high sensitivity, MRI is also suitable in detecting focal bone marrow disease. For these cases a biopsy of these focal bone marrow lesions can be performed in order to stage the disease properly as in the presence of neuroblastoma or malignant lymphoma presenting with localized disease, however, with focal bone marrow metastases on MRI. In addition MRI can also be used to follow up the disease as well as therapy by showing the regression of these bone marrow lesions.

Adrenal Gland Neoplasms↗

[Functional diagnosis of biliary endoprostheses using hepatobiliary sequence scintigraphy].

In 11 patients with biliary endoprosthesis, hepatobiliary scintigraphy with dimethyliminodiacetic acid (HIDA) was performed 16 times because of an increase in the serum bilirubin level. For the demonstration of dysfunction of the endoprosthesis, this method proved to have the same sensitivity as transhepatic cholangiography, which was performed as control examination. Therefore, hepatobiliary scintigraphy, a noninvasive and well-tolerated examination, can be recommended as a primary diagnostic tool in addition to ultrasonography for assessment of the drainage function of the biliary endoprosthesis.

Aged↗

[Results of bone marrow scintigraphy in hematological diseases].

Bone marrow scintigraphy was performed in 40 patients with haematological disorders (lymphomas, multiple myeloma, myeloid leukaemia, panmyelopathy and others). Routine skeletal scintigraphy was available for comparison in 18 patients. In agreement with the literature it became evident that marrow scintigraphy can show infiltrations of the bone marrow in haematological disorders earlier than skeletal scintigraphy. Hot lesions were caused by reactive proliferation of the bone marrow such as may occur with acute inflammatory joint diseases, osteomyelitis, fracture healing or other entities. Marrow imaging demonstrated reliably the actual distribution of the functioning bone marrow, a characteristic that is important for diagnosis and staging, especially in myeloproliferative diseases.

Bone Marrow↗

[Combination radiochemotherapy in the limited-disease stage of small-cell bronchial carcinoma. Results following high-dosage radiotherapy].

From 1980 through 1984, 72 patients with small cell bronchial carcinomas were treated by radiotherapy. Twenty-one patients who were in a limited disease stage (LD) received chemotherapy according to the ACO scheme and high-dose radiotherapy with 50 Gy. These patients had a complete remission rate of 67% and a partial remission rate of 33%. The median control period was 37 months. At the time of diagnosis, patients had a median survival time of ten months (six to 36 months). A recurrence in the irradiated region was seen in none of the patients, however, 14% of patients developed a recurrence beyond the irradiation field. The results are compared to literature and discussed.

Adult↗

[Multiple lymphomatous polyposis of the intestinal tract].

The authors report on a patient suffering from centrocytic non-Hodgkin's lymphoma. Double contrast examination of the colon showed multiple, partially pedunculated polyps in the terminal ileum and colon. As cause of these lesions involvement of the bowel by lymphoma could be proved by biopsy. The differential diagnosis against other types of polyposis is discussed and the variable radiographical manifestations of the disease known as "multiple lymphomatous polyposis" are pointed out.

Adult↗

[Serous cystadenocarcinoma of the ovary: unusual visualization of calcified intraperitoneal metastases in CT and bone scintigraphy].

In a 45-year old patient with serous cystadenocarcinoma of the ovary CT showed small calcifications in metastases along peritoneal surfaces. These "psammoma bodies" indicated abdominal implants, which in other respects would not have been demonstrable via CT scans because of their small size. During bone scintigraphy the calcifications caused unusual extraskeletal focal uptake of 99mTc-MDP in the abdomen.

Bone Neoplasms↗

[Agenesis of the inferior vena cava].

A case of agenesia of 3 of the 4 segments the vena cava inferior is presented. The embryogenesis of the v. cava inferior is discussed in so far as is relevant for the malformation in this case. Exact diagnosis and classification can be made via intravenous and intraarterial DSA and computed tomography.

Adult↗

Parathion and gastrointestinal transit in the rat.

The possibility of in vivo or post-mortem acceleration of gastrointestinal transit was investigated in the rat after sublethal or lethal doses of the insecticide parathion. Parathion did not change gastrointestinal transit time before or after death in the poisoned rat.

Animals↗

[On the evidential value of diatoms in cases of death by drowning (author's transl)].

With the aid of experiments in animals we have again investigated the question as to the quantitative and qualitative immigration of diatoms into the greater circulation and thus into the bone marrow at the time of drowning. We have applied an experimental method which meets this complex topic. Thus, just before the animals (rabbits) were drowned, one of their hind legs was amputated, and the vessels of one of their kidneys were clamped to learn how many diatoms were present before the drowning. After the drowning, a qualitative and quantitative examination of the bone marrow of both hind legs and of both kidneys was carried out. In all cases, an increase in the number of diatoms could be recorded as compared to the initial number of diatoms present prior to the drowning. Based on the results of the experiments and the information gained in the examinations criteria are discussed which, when applied, allow positive diatom findings to indicate valuable diagnostic information about death by drowning. References is made to preservation of the death causing liquid in the stomach.

Animals↗

MR-imaging with Gd-DTPA in carcinomas of tongue, oro- and hypopharynx.

High-field MRI was performed in a series of 24 patients with squamous cell carcinomas of the tongue, oro- and hypopharynx. The value of contrast enhanced T1-weighted images in tumor staging was established prospectively. Non-contrast T1-weighted images did not provide sufficient tumor-delineation. Marked contrast enhancement produced by Gd-DTPA was observed in all carcinomas and in normal pharyngeal mucosa. In tumors of the tongue and upper pharynx clinical examination and ultrasound were equally sensitive as post-contrast MRI; in tumors of the lower pharynx the true tumor extension could be better assessed by contrast-enhanced MRI.

Adult↗

Endoscopic removal of an intraorbital "tumor": a vital surprise.

We present the first case report of an endoscopic removal of a living worm, species Dirofilaria repens, from the orbital cavity. As of today, over 410 cases of Dirofilaria repens infections in man are recorded in world literature, six of which were localized in the orbital cavity. In Austria we know of four cases of an infection with this parasite, but none in the orbit. Dirofilaria repens is widespread only in the Old World, particularly in Southern and Eastern Europe, in Asia Minor, and in Central and Southern Asia. The highest prevalence of the disease is recorded in Italy (181 cases). In clinical practice, the infections have mostly been misdiagnosed as a neoplasia, usually benign but sometimes malignant. Under the assumption of an intraorbital tumor, the endoscopic transnasal revision of the orbital cavity was performed, as this approach promised to be least traumatic and best suited for the lesion, resulting in complete removal of the live worm. In unclear lesions in the head and neck, and infection with Dirofilaria repens should be considered as a differential diagnosis.

Austria↗

MR findings in methotrexate-induced CNS abnormalities.

MR of the brain was performed in eight patients (mean age, 14.9 years) with osteogenic sarcoma during or after IV treatment with high-dose methotrexate. MR detected brain abnormalities in four patients, three of whom had concomitant neurologic dysfunction. Pathologic findings demonstrated on MR were (1) chronic brain edema, demonstrable over a period of 3-14 months (proved by autopsy in one patient); (2) multifocal white matter necrosis; and (3) deep brain atrophy. MR appears to be valuable in the detection of abnormalities induced by treatment with high-dose methotrexate.

Adolescent↗