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Biomedical subjects

G Reboul

Publications and source records attributed to G Reboul.

14 recordsLinked to original sources

Conservative treatment for postintubation tracheobronchial rupture.

BACKGROUND: Postintubation tracheobronchial rupture is usually responsible for unstable intraoperative or postoperative conditions, and its management is discussed. We insist on conservative treatment as a viable alternative after late diagnosis of postintubation tracheobronchial rupture. METHODS: We conducted a retrospective study including 14 consecutive patients treated between April 1981 and July 1998. RESULTS: Twelve tracheobronchial ruptures occurred after intubation for general surgery and two after thoracic surgery. In all cases, the tear consisted of a linear laceration of the posterior membranous wall of the tracheobronchial tree ranging from 2 to 6 cm. One death occurred in a very weak patient unfit to undergo a redo operation for surgical repair. Seven patients were treated conservatively and cured without sequelae. Six patients underwent surgical repair, of whom 2 were diagnosed and repaired intraoperatively. CONCLUSIONS: Aggressive surgical repair is not always mandatory after delayed diagnosis of iatrogenic tracheobronchial rupture. Conservative treatment must often be considered, except after lung resection.

Adult↗

[Villous adenoma of the duodenum. Apropos of a case].

We report a case of recurrent villous tumors (1989-1995) of the second duodenum. The diagnosis of these rare tumors was obtained by endoscopy. Risk of recurrence and degeneration raise the question of surgical or endoscopic treatment.

Adenoma, Villous↗

[Dynamics of infestation with gastrointestinal strongyles of moors grazed by sheep in the Mediterranean area].

The dynamics of free-living stages of sheep Nematodes was studied. The kinetics of infective larvae population was established during 16 months by sampling grass and faeces every 2 wk on an area frequently used by ewes on 3 out of 4 paddocks grazed by a flock. The periods at high risk for animal infection were autumn and spring, the moors being sterilized during summer by the dryness. Teladorsagia circumcinta, Trichostrongylus vitrinus, Nematodirus filicollis and N. spathiger were the main species. Free-living populations were quantified during the grazing seasons on 2 out of the 5 paddocks grazed by a second flock. Herbage and faeces were sampled on 12 areas from each paddock. Deposited eggs on each area were calculated at each rotational cycle by coproscopy and by estimating the amount of faeces deposited on the ground. Faeces appeared to be the main reservoir of infective larvae during the dry periods of spring and autumn. With rainfall the larvae were liberated from faeces and the populations on herbage increased steeply. The distribution of larval populations on the moor were highly correlated to the distribution of the eggs deposited during the preceding grazing cycle.

Animals↗

[Chemotherapy of embryonal carcinoma of the testis with lymph node invasion and/or pulmonary metastases. Results of a VBP type protocol].

Fourteen patients with histologically proven embryonal carcinoma of the testis with pulmonary metastasis (10 pts) or para-aortic nodal involvement (4 pts) were treated by a chemotherapy regimen including vinblastine, bleomycin and cisplatin. Extreme ages were 19 and 51 years with a median age of 32 years. Median duration of treatment was 6 months (6 cycles of chemotherapy) without maintenance treatment. After completion of chemotherapy, 6 patients in complete remission received para-aortic node irradiation (45 Grays in 25 fractions). One patient had a para-aortic node dissection, histologically negative. With a median follow-up of 47 months (maximum 92 months, minimum 12 months), eleven patients are in complete remission (78.6%). Three patients are dead from the disease, in spite of salvage chemotherapy. There were no toxic deaths. Disease-free actuarial survival is 74% at 4 years. Our results confirm the excellent therapeutic results of this chemotherapy regimen in embryonal carcinoma of the testis with pulmonary metastasis and/or para-aortic nodal involvement.

Adult↗

[A study on 333 patients with adenocarcinoma of the endometrium treated by combined surgery and radiation therapy (author's transl)].

Three hundred and thirty-three consecutive patients with adenocarcinoma of the endometrium treated from 1958 to 1978 by combined surgery and radiation therapy or radiation therapy alone were reviewed. According to the FIGO staging system, there were 204 stage I, 40 stage II, 24 stage III and 20 stage IV. 40 cases of recurrences were also included in this study. The main parameters influencing survival were clinical staging, depth of myometrial invasion, histologic differentiation as well as the possibilities of radical surgery in these patients. Analysis of therapeutic results shows the superiority of pre-operative intra-cavitary irradiation followed by total abdominal hysterectomy and bilateral salpingo-oophorectomy with an 80% actuarial survival at five years in stage I. Primary surgery followed by radiation therapy gives inferior results, particularly in stage II. Treatment by radiation therapy alone should be reserved for inoperable patients after careful evaluation and gives a 35% actuarial survival at five years. The incidence of serious therapeutic complications was 3,6 %. The early diagnosis of endometrial carcinoma by means of systematic endo-uterine explorations in post-menopausal bleeding and the elaboration of combined multi-modality protocol prior to any treatment should lead to a better cure rate for this cancer of increasing incidence.

Adenocarcinoma↗

[Not Available].

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Balneology↗

[Hodgkin's disease and pregnancy].

The onset of pregnancy raises special problems during Hodgkin's disease and renders difficult full assessment of the extent of the disease. Furthermore acute exacerbations are fairly common, except in patients with a complete remission for more than two years. The critical period seems to be labour and the following weeks. In fact when pregnancy occurs during Hodgkin's disease, one may decide to interrupt it. However, if the patient has been in remission for more than two years, one may allow the pregnancy to continue. The decision will be taken in the light of each case. After pregnancy contraception should be advised in all women with Hodgkin's disease.

Abortion, Induced↗