Long term experience in the treatment of advanced prostatic cancer with decapeptyl, compared to orchiectomy.
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Biomedical subjects
Publications and source records attributed to G Renders.
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A case of true hermaphroditism with hydrocolpos in a 7-month-old infant is presented. This is, to the authors' knowledge reported case of association of both anomalies. Hydrocolpos is a clinical entity characterized by vaginal distension with accumulation of fluid, which can cause respiratory embarrassment and urinary, intestinal and circulatory obstruction. It is a condition of great rarity. It is usually detected in the neonatal period, although it has been reported in older children, and it calls for urgent treatment. True hermaphroditism is a rare form of intersexuality, which can only be considered to exist if both male and female elements can be identified in the gonad.
Cold knife optical urethrotomy with the Sachse urethrotome was used in 44 patients with urethral strictures. Appraisal if the results, after a mean follow-up of fourteen months, showed 77.3 per cent success rate regarding urine flow rates and 81.8 per cent regarding subjective response of the patient.
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The treatment of 10 cases of Peyronie's disease with procarbazine, a cytotoxic drug, is presented. The results were disappointing.
Sulphamethoxazole and trimethoprim concentrations were measured in 19 enucleated human prostate glands. Good concentrations of sulphamethoxazole were found after 4 days of treatment: the ratio of plasma concentration to that of prostate varied from 1-25 to 3-29. The trimethoprim concentrations were 2 to 3 times higher in the prostate than in the plasma. These high concentrations were reached very rapidly after the first dose of trimethoprim. The results are compared with date from the literature. The combination sulphamethoxazole-trimethoprim should be of value in the treatment of bacterial prostatitis.
3 cases of ureteric obstruction secondary to aortic femoral bypass grafting are presented. This complication has been infrequently reported and we feel that it may be more common than is recognised. In all other published cases the ureter lay behind the prosthesis but the authors present a surgically proved case where the ureter lay in its normal position. The aseptic vascular reconstructive surgical procedures are to be preferred to ureteric reconstruction.
We have presented 3 cases of ureteral obstruction secondary to aortic femoral by-pass grafting. This complication has not been frequently reported and we feel that it may be more common than recognised. In all the other published cases the ureter was passing behind the prosthesis but the authors present a surgically proved case where the ureter lies in its normal position. They also prefer the aseptic vascular procedures for reconstruction.
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