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Biomedical subjects

G Righetti

Publications and source records attributed to G Righetti.

11 recordsLinked to original sources
PubMed1991

Serum selenium and precursors of cardiovascular risk factors in adolescents.

The aim of this study was to determine, in a population of Italian adolescents, the association of serum selenium levels with precursors of biochemical and anthropometric variables known as being among the major risk factors for cardiovascular diseases in the adult population. The following measurements were taken in a school sample of 627 adolescents (aged 12-13 years); serum selenium, total cholesterol, high density lipoprotein cholesterol, non-HDL cholesterol, height, weight, body mass index, systolic blood pressure and diastolic blood pressure. The serum selenium levels were slightly higher in males (83.1 +/- 10.1 micrograms/l) than in females (81.7 +/- 11.0 micrograms/l), but the difference was not statistically significant. Serum selenium was positively correlated with total cholesterol, diastolic blood pressure and HDL cholesterol in both sexes; moreover it was positively correlated with non-HDL cholesterol and negatively correlated with height in males only.

Adolescent↗
PubMed1991

Air in the main pancreatic duct: demonstration with US.

Air in the pancreas--nearly always related to an abscess or a pancreatic fistula--is rarely demonstrated. Over a 3-year period, the authors detected air in the main pancreatic duct with ultrasonography (US) in 11 patients. The ductal caliber was normal in five patients and dilated in six. At US, air in the main pancreatic duct is characterized by strongly echogenic foci or echogenic lines in the duct, casting acoustic shadows or producing reverberation artifacts. It is likely that in patients who have biliary-enteric anastomoses or have undergone sphincterotomy, air in the duct of Wirsung is the result of biliary-pancreatic reflux. In patients who have not undergone such operations, the likely cause of pancreatic gas is duodenal-pancreatic duct reflux. Pancreatic gas may be related to causes other than a pancreatic abscess or fistula; it is therefore important for clinicians to realize that pancreatic ductal gas seen on US images may be secondary to prior surgery or due to sphincter of Oddi dysfunction.

Adult↗
PubMed1990

[L-carnitine for the treatment of acute myocardial infarct].

The treatment with L-carnitine in acute myocardial infarction was tested in 146 patients admitted in a coronary care unit. The administration of L-carnitine was based upon the drug availability and did not occur at random. Altogether 49 patients received the drug and 97 served as controls. By comparing the clinical characteristics at hospital admission a worse prognosis could be expected in those who did not receive the drug. Within 28 days from admission no deaths were observed in the treated group whereas 18 deaths (18.6 percent) were recorded among the controls. The prediction of fatal events was estimated by multiple logistic function taking the 28-days mortality as end point (either including or excluding the 72 hours early deaths) and using 2 different sets of factors as possible predictors, including the use of the drug. In particular there were 18 factors usually claimed as determinants of short term prognosis and 9 factors which were shown statistically different between the 2 groups. In all the 4 solutions the coefficient of L-carnitine was negative and in 3 of them also statistically significant, suggesting the protective role of the drug against early fatalities. Only the coefficient of the clinical impression of severity showed a greater statistical significance. The reported observations can be defined as the results of a pilot study which justify a more systematic study of the drug in the acute phase of myocardial infarction.

Adult↗
PubMed1979

Atrial repolarization: its role in ST elevation.

In four patients, ectopic supraventricular rhythm (or beats) with cephalad anomalous atrial activation and, generally, a short PR, were always associated with an ST elevation in the leads with a negative P wave. An inverted Ta wave appears to be responsible for the ST elevation.

Adult↗
PubMed1979

[The causes of death after acute myocardial infarction (author's transl)].

Following a brief outline on problems concerning methodology, the cause of death is analysed in 110 patients dying from acute myocardial infarction during hospitalization. Autopsy studied were carried out in 78 cases. Of the various causes, the most frequent were forms of contractile insufficiency (EPA, shock, shock + EPA, biventricular congestive heart failure) which were responsible for 50.90% of cases; followed by cardiac rupture (considered in a single group with electromechanic dissociations of the patients not submitted to autopsy studies since in the experience of the Authors cardiac rupture almost always presents with this pattern) with a frequency of 29%. The frequency of arrhythmias, on the other hand, is very low, particularly in the coronary care unit where it is practically a negligible causa mortis 2.72%): even if sudden death, in patients who were not monitored, is included amongst the arrhythmias, the percentage is still only about 10%. Embolism (usually pulmonary, but systemic in one case) was the cause of death in 5 patients (4.54%). Three patients over 80 years of age died from ischemic cerebral episodes. Age, sex, and site of infarction, do not appear, in the present series, to have a determinant effect in the cause of death; a higher frequency of rupture in the female sex was not, for example, confirmed. On the basis of the observations in the present series, any relationship between cardiac rupture and anticoagulating therapy, steroid treatment, application of endocavitary stimulators, or early ambulation is excluded. It is also excluded that reanimation, as hypothesized by some Authors, may be responsible for rupture.

Acute Disease↗