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Biomedical subjects

G Rooth

Publications and source records attributed to G Rooth.

35 records · Page 2Linked to original sources

Effect of respiratory physiotherapy on arterial oxygen tension.

The effect of deep breathing on arterial oxygen tension was investigated in 45 postoperative patients. Arterial oxygen tension was estimated by the transcutaneous oxygen tension method, which allows continuous non-invasive measurement of the arterial oxygen tension changes. Three deep breaths in 1 min, assisted by three respiratory therapy devices, were compared to a standard physiotherapy programme. A peak increase in arterial oxygen tension of 3--4.5 mmHg occurred after 1 min, and significantly increased values were seen for 2--4 min following deep breathing with the three respiratory devices. From the various physiotherapeutic procedures, verbally and manually assisted deep breathing gave a 7 mmHg PO2 peak and significantly increased values for 6 min. The sign mechanism is discussed in the light of the present knowledge of airway closure, which gives a satisfactory explanation of the short-lasting increase in oxygen tension.

Closing Volume

[Asphyxia].

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Acidosis

Posterolateral diaphragmatic hernia--long-term results.

During the years 1965--1974, 125 cases of posterolateral diaphragmatic hernia have been operated at five departments of pediatric surgery in Sweden. The overall operative mortality was 50%. A follow-up investigation included 19 cases, where in 12 cases spirometry and in 11 cases studies of the mobility of the diaphragm were included. Physical examination revealed excellent results in most cases. Lung function studies, however, show a moderate (20--30%) reduction, which is not surprising with regard to lung hypoplasia and impaired movement of the diaphragm on the operated side. In adolescence and younger age, these patients are mostly in excellent condition; but later, when lung function is also reduced by the age factor, their neonatal condition may be of importance.

Adolescent

Transcutaneous PO2 measurements in seriously ill newborn infants.

Continuous monitoring of oxygen tension using the transcutaneous electrode developed by Huch and co-workers was studied in severely ill newborn infants. Acceptable results were obtained despite the theoretical possibility that vasoconstriction might interfere with the method when used in the very ill. The reliability and clinical usefulness of the method is illustrated in 4 cases of severely ill newborn infants.

Acute Disease

Influence on fetal carbohydrate and fat metabolism and on acid-base balance of glucose administration to the mother during labour.

Parturients during normal labour were given glucose. The maternal-fetal difference of glucose increased with increasing maternal glucose level. Glucose load caused a rapid early response of maternal insulin release. A parallel rise in plasma lactate and pyruvate occurred in both fetus and mother. The basal maternal hydroxybutyrate and glycerol concentrations decreased significantly during glucose load. The study demonstrated that at term, components of lipid metabolism in fetal and maternal plasma-in contrast to glucose -vary independently. No major disturbances of the fetal acid-base balance were found.

Acid-Base Equilibrium

Transcutaneous oxygen tension measurements in newborn infants.

Attention is called in this brief review article to the development and clinical uses of a new technique for monitoring blood oxygen tensions in newborn infants. This technique uses an electrode recently developed by Huch et al. in Germany to measure arterial oxygen tensions directly through the skin. This device allows for continuous monitoring with a non-invasive technique. The method is now in use in European hospitals. Clinical experiences are cited to document its usefulness.

Blood Gas Analysis

Exhibitionism.

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Adolescent

Frontiers in perinatal medicine.

A few of the topics of particular interest in perinatal medicine such as surfactants, erythropoietin, cordocentesis and computer assisted decision support are briefly reviewed. Asphyxia and oxygen toxicity are discussed as is the increase in the formation of free radicals which is part of reoxygenation. The infinitely larger problem of the poor in developing countries can best be improved--at least partially--by extending family planning techniques universally, otherwise the population explosion will counteract any other improvements.

Asphyxia Neonatorum

The validity of the transcutaneous oxygen tension method in adults.

The transcutaneous oxygen tension (tcPo2) in five healthy subjects and in seven patients was monitored continuously by the technique of Huch, Huch, and Lübbers. The inspired oxygen concentration was varied between 15 and 100%. Once stable tcPo2 recordings were obtained, blood samples were drawn via an indwelling arterial catheter for oxygen tension (Pao2) determination. A comparison between the Pao2 and the tcPo2 values is illustrated graphically. There was a small difference between these values in the healthy subjects, which was attributed to variations in the skin from subject to subject. In the patients, a circulatory factor may have added to differences in the absolute levels. The coefficient of correlation between Pao2 and tcPo2 was in all cases higher than 0.98. In healthy persons, Pao2 may be predicted from tcPo2. In patients, any change in Pao2, due to deterioration or improvement, is manifested in the tcPo2 curve. If one or two arterial blood measurements are performed, low as well as high Pao2 values may be predicted from tcPo2 in patients without gross circulatory impairment.

Adult