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Biomedical subjects

G Rusu

Publications and source records attributed to G Rusu.

At least 19 recordsLinked to original sources

[The debut of Jennerian vaccination in the mining regions of Transylvania].

The first attempts at vaccination by Jenner's method in Transylvania (Romania) were made in 1801; vaccination became compulsory in 1808. By researching the mining archives, details about the evolution of vaccination activities were found. The most important are: the initiative of the surgeon Peter Molnar from Sacaramb (June 1801), the first vaccinations performed by the chief medical officer of the mining area (November-December 1801), the consistent reporting of vaccination, payment of the vaccinator surgeons, vaccination promotion and means of providing vaccination material.

Communicable Disease Control↗

Conjugal transfer of plasmids and antibiotic resistance among Escherichia coli isolated from animals in a rural area in Sarawak (Malaysia).

Thirty-six strains of Escherichia coli isolated from animals in Bario, a remote area in Sarawak, Malaysia, were examined for presence of plasmid DNA and their susceptibility to nine antimicrobial agents. Of the total 36 isolates, five bovine and six canine isolates were found to contain plasmid DNA ranging in sizes from 2.6 to 70 kilobases. All were susceptible to chloramphenicol, erythromycin, gentamicin, nalidixic acid and neomycin but resistance to ampicillin (47%), erythromycin (19%), streptomycin (25%) and tetracycline (11%) was observed. Resistance was associated with carriage of a 47 kb (SC98), 70 kb, (SC133) and 56 and 4.6 kb (SC119) plasmids which were transmissible to the Escherichia coli K12 recipient. It is concluded that animals form a potential reservoir of R plasmids carrying E. coli in the study area.

Animals↗

[Not Available].

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History, Modern 1601-↗

[Fluoroquinolones. Drug interactions].

This review summarizes clinically relevant drug-drug interactions for fluoroquinolones: antiacids containing aluminum and magnesium salts, iron or zinc preparations, sucralfate, cimetidine, ranitidine, warfarina, cyclosporin, rifampin, oral contraceptive steroids, benzodiazepine, probenecid, beta-lactam antibiotics, nonsteroidal anti-inflammatory drugs, metronidazole, theophylline, caffeine.

Animals↗

[The synthesis and anti-inflammatory properties of 7-theophyllineacetic acid derivatives].

Some esters of 7-theophyllinylacetic acid were synthetized, characterized physicochemically and tested for their anti-inflammatory properties. As compared to indomethacin, reference anti-inflammatory drug, all synthetized compounds were less toxic. The anti-inflammatory properties are influenced by the nature of the ester group radicals, the more active having ramified alchils.

Animals↗

T and B lymphocytes in respiratory pollen allergies (bronchial pollen asthma and allergic rhinitis).

The T and B lymphocytes were identified by means of the rosette tests in the peripheral blood of 79 patients with respiratory allergies of whom 41 with allergic rhinitis and 38 with bronchial pollen asthma, as well as in 16 control subjects. The results have shown a clear lessening of the T cells (both in per cent and absolute values) and a less significant decrease of the B cells (only in absolute values) in the patients as compared with the controls. These data suggest an immune deficiency which did not differ between the two groups of patients and was not influenced by the specific hyposensitizing treatment.

Adolescent↗

Statistical methods for longitudinal study of risk factors in cardiovascular diseases.

The purpose of this paper is to study the risks of developing a cardiovascular disease, under conditions of primary prevention. The risk factors were studied as a synthetic index, representing a linear weighted combination, called by us prognostic index. For the longitudinal study and prediction the multiple regression analysis was used.

Adult↗

Studies on the familial character of endemic Balkan nephropathy. Possible role of the toxic hydric factor in the determination of "familial agglomerations" in endemic Balkan nephropathy.

The study was carried out in an attempt to explain the familial character of endemic Balkan nephropathy and of agglomeration of cases in certain households and in the ascendency of certain families. The hypotheses of a genetic disease or that of an infectious etiology have been taken into consideration in previous studies - by chromosomal analyses and statistical-mathematic tests of contagiousness - without being able to find arguments in support of one or the other hypotheses. This study brings important elements in favour of the possible role of ecologic factors and mainly of the hydrictoxic one, in the determination of the familial agglomerations in endemic nephropathy. Thus using radionuclear determination methods, we could demonstrate in a locality of the endemic area that around the water sources with high content of nephrotoxic oligoelements (cadmium, chromium, manganese, cobalt) there are more diseased families than around water sources poorer in these oligoelements.

Balkan Nephropathy↗

Application of mathematical methods to the study of familial aggregation in endemic nephropathy. I. The hypothesis of infectious etiology.

Among many etiological factors, infection and the genetic factor are the main two causes which could explain the familial aggregation of endemic nephropathy (EN). The data collected over all the EN cases during 1957--1976 in the endemic village Bistriţa have been analysed for time-space clustering and a particular type of spatial clustering (within household) by the Knox's space-time interaction test and Walter's pair statistic test. The lack of clustering could be interpreted as suggesting the lack of infection (human transmission pattern) in the occurrence of endemic nephropathy.

Humans↗