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Biomedical subjects

G S Benson

Publications and source records attributed to G S Benson.

At least 19 recordsLinked to original sources
PubMed1991

Intraoperative decision-making in renal trauma surgery.

Surgery for renal trauma requires three intraoperative decisions: Should the kidney be explored? Is pedicle control necessary? What procedure should be performed? In 85 explorations for penetrating (66) and blunt (19) trauma, we found that penetrating injuries, active hemorrhage, or major tissue destruction are reasons for mandatory renal exploration. This resulted in 26 nephrectomies, 9 partial nephrectomies, and 4 major renorrhaphies. Forty-six patients underwent minor renorrhaphy or needless exploration without complications. Formal pedicle control was carried out 33 times (39%), but it was never necessary to control parenchymal hemorrhage. Unless a wound overlies the great vessels, perirenal hematomas can be safely entered laterally without prior pedicle control using manual pedicle or parenchymal control if needed.

Adolescent↗
PubMed1990

Bladder dysfunction in the elderly.

Bladder dysfunction in the elderly is an enormous public health problem. Laboratory research using animal models has to date not yielded clinically useful new information. Demographic and urodynamic studies in selected elderly patients indicate that neurological disease and bladder outlet obstruction are the primary causes for voiding dysfunction. The effect of aging per se on the urinary bladder is not known. Elderly patients who have bladder dysfunction should be evaluated with a careful history and physical examination combined with a practical urodynamic evaluation rather than simply being labeled as having "bladder dysfunction in the elderly."

Aged↗
PubMed1990

Mixed density lesion of the anterior maxilla.

A case of COC which developed as a mixed lucent-opaque lesion in the anterior maxilla of a young person is discussed from the standpoint of clinical and radiographic differential diagnosis. Current concepts of the pathology of the COC and EOGCT are discussed.

Adolescent↗
PubMed1979

Autonomic innervation of the mammalian penis: a histochemical and physiological study.

The distribution of adrenergic and cholinergic nerves was studied in penile tissue from rat, rabbit, cat, monkey and man. Glyoxylic acid histofluorescence and acetylcholinesterase-positive fibers were found in all tissues examined, but histofluorescent, presumably adrenergic fibers predominated. In general, except in the rabbit, more nerve fibers of both types were found in the corpus cavernosum (CC) than in the corpus spongiosum/penile urethra (CS). The rabbit penis showed slightly more adrenergic fibers in the CC than in the CS and more cholinergic nerves in the CS than in the CC. The CC of the monkey demonstrated an alpha receptor mediated contractile response to norepinephrine (NE) stimulation and no response to acetylcholine (ACh) in an in vitro muscle bath.

Acetylcholinesterase↗
PubMed1979

Transient blindness: unusual initial symptom of transurethral prostatic resection reaction.

Transient blindness was seen in 2 patients undergoing transurethral resection (TUR) of the prostate as the initial symptom of a severe TUR reaction. Cerebral edema of the occipital cortex is the most probable mechanism. Both fully recovered their vision when appropriately treated. Patients with visual disturbances during transurethral prostatectomy should be suspected of having a TUR reaction.

Aged↗
PubMed1979

Gross hematuria associated with sickle cell trait and von Willebrand's disease.

A case of recurrent gross hematuria, sickle cell trait and von Willebrand's disease is reported. The gross hematuria abated promptly after the institution of cryoprecipitate therapy. The importance of considering von Willebrand's disease in the differential diagnosis in patients with sickle cell trait and hematuria is discussed.

Adolescent↗
PubMed1979

Lack of evidence for adrenergic innervation of the external urethral sphincter.

Catecholamine histofluorescence studies of the external urethral sphincter in 11 normal dogs, 4 dogs treated with tranylcypromine and 4 humans have demonstrated that this striated muscle does not possess adrenergic innervation. This finding suggests that the sympathetic nervous system affects outlet resistance only through its influence on the smooth musculature of the bladder neck and urethra.

Animals↗
PubMed1978

The reproducibility and interpretation of carbon dioxide cystometry.

The day-to-day and same-day variability of carbon dioxide cystometry was examined in a population of men. Considerable variability was observed in each parameter monitored. The implications of such variability, and the validity and significance of certain cystometric events are discussed.

Adult↗
PubMed1977

Bladder muscle contractility. Comparative effects and mechanisms of action of atropine, propantheline, flavoxate, and imipramine.

The anticholinergic and antispasmodic activity of atropine, propantheline, imipramine, and flavoxate were judged by each drug's ability to inhibit bethanechol chloride and barium chloride-induced canine detrusor contractions. In this in vitro model, atropine and propantheline are pure anticholinergic agents. Imipramine significantly decreases both bethanechol and barium-induced contractions, while flavoxate only minimally inhibits the response to either stimulant.

Animals↗
PubMed1976

Innervation of trigonal area of canine urinary bladder.

Adrenergic and cholinergic histochemical staining techniques and in vitro muscle strip responses to adrenergic and cholinergic stimulation and blockade have failed to demonstrate any neuromorphologic or neuropharmacologic differences between the musculature of the canine trigone and that of the underlying detrusor. There is no evidence to suggest that a functional potential could be attributed to the trigone separate from that of the related bladder base.

Acetylcholine↗
PubMed1976

Management of neurogenic bladder dysfunction in the adult.

A review of the management of neurogenic bladder dysfunction in the adult is presented. The various modes of therapy are classified according to their effects on bladder contractility and outlet resistance, providing a logical framework for discussion.

Autonomic Nerve Block↗