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Biomedical subjects

G S Chubak

Publications and source records attributed to G S Chubak.

8 recordsLinked to original sources

Topical nylidrin and aqueous humor dynamics in rabbits and monkeys.

Topical administration of nylidrin hydrochloride lowered intraocular pressure in both albino rabbits and cynomologus monkeys. The maximum decrease occurred two hours following drug application and was unilateral. The response lasted four hours in monkeys and at least six hours in rabbits. Outflow facility, episcleral venous pressure, and aqueous humor flow measured by fluorophotometry were unaltered in both species. In rabbits in the treated eyes, ocular blood flow was increased, and anterior and posterior chamber ascorbate concentrations were unchanged. The mechanism of IOP reduction appears to be increased aqueous humor outflow via uveoscleral outflow routes that are not pressure dependent.

Administration, Topical

New techniques in fundus examination: II. A new simplified technique for binocular indirect ophthalmoscopy.

A new technique of binocular indirect ophthalmoscopy uses a Finhoff transilluminator, held between the observer's eyes, as the light source. The light is focused in the patient's dilated pupil through a condensing lens in a darkened room and the image is seen stereoscopically. The advantages and limitations of this technique and the optical principles are highlighted.

Fundus Oculi