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Biomedical subjects

G S Dunaev

Publications and source records attributed to G S Dunaev.

6 recordsLinked to original sources

[Production of L forms of the plague microbe].

Experiments were conducted in vitro. The process of formation of unstable L-form cultures of Pasteurella pestis under the effect of penicillin was studied. A comparatively high frequency of this phenomenon in various strains was demonstrated. A possible role of the L-transformation process in the persistence of the causative agent in the organism of wild animals in endemic foci of infection is put forward.

Culture Media

[Pathogenicity of nonagglutinating vibrios].

In studying the pathogenicity of nonagglutinating vibrios it was established that the majority of the strains isolated from the patients suffering from enteritis possessed enteropathogenic properties which were revealed in the trials on nursling rabbits and on the isolated intestinal loop a of an adult rabbit. In difference to the cholera vibryos, these microorganisms produced no typical cholerogenicity syndrome expressing, however, a number of enteropathogenic properties: caused diarrhea, overfilling of the intestine with fluid, etc. Autopsy showed a typical enterocolitis picture, confirmed by histological studies. Nonagglutinating vibrio cultures isolated from the water and from healthy persons possessed no enteropathogenic properties. An isolated intestinal loop of an adult rabbit proved to be the most sensitive experimental model.

Animals