PubMed Health⌕ Search

Biomedical subjects

G S Graham

Publications and source records attributed to G S Graham.

At least 19 recordsLinked to original sources
PubMed1989

Effects of canine versus molar occlusal splint guidance on nocturnal bruxism and craniomandibular symptomatology.

The use of interocclusal orthopedic appliances is the most common method for managing nocturnal bruxism and associated craniomandibular symptoms. Yet there is no consensus on the mechanism of action or best design for optimal clinical results. Posterior disocclusion through canine or anterior guidance is believed to be a key feature. The purpose of this study was to compare a canine versus molar guidance appliance in eight chronic bruxist patients. The appliances were used for 10 to 14 nights. The two appliances provided nearly equivalent effects on nocturnal bruxism in seven of eight subjects. Clinical examination and subjective pain ratings did not differ with the two guidance patterns. These results question the common assumption that canine guidance is a critical design feature for the management of nocturnal bruxism and associated craniomandibular symptoms.

Adult↗
PubMed1988

Fibrolipoma of the gingiva. A case report.

A case of gingival fibrolipoma is described. The lesion presented as a tumor-like mass with a broad base arising from the attached gingiva adjacent to the mandibular left first bicuspid. Microscopic evaluation of the lesion revealed an admixture of mature adipose tissue and fibrous connective tissue. Fibrolipomas are an infrequent variant of lipomas. A review of the literature indicates that a gingival location for such lesions is rare.

Adult↗
PubMed1988

Decontamination: a microbiologist's perspective.

The primary objective of decontamination is to protect healthcare workers who handle medical devices from infectious diseases that may be present on those devices. Ideally, the decontamination process should provide both cleaning and biocidal activity. A wide range of equipment, from automatic washer/sterilizers to semi-automated washer/sanitizers are commercially available to satisfy this need. The primary difference between these pieces of equipment, from a microbiology perspective, is in the level of safety they provide. A summary comparison of the decontamination methods is shown in Table 1. Without a doubt, steam sterilization as a method of decontamination provides a greater safety level than may be required. However, the question is, "Do disinfection and sanitization provide an adequate safety level?" Although items do not necessarily need to be sterile to be safe to handle, sterilization processes provide the greatest margin of safety because of the significant microbial lethality and the ability to effectively monitor the process via biological indicators. Sterilization effectively eliminates the concern regarding the nearly unanswerable question of bioburden. Unfortunately, not all items are capable of being processed through a washer/sterilizer. Therefore, consideration must be given to the process compatibility of each device. Disinfection processes provide the next level of safety. Unfortunately, there is no recognized or accepted method for quantitatively describing or monitoring a thermal disinfection process. As is the case with sterilization consideration must be given to the process compatibility of each device. Sanitization provides the lowest level of safety for the decontamination process.(ABSTRACT TRUNCATED AT 250 WORDS)

Central Supply, Hospital↗
PubMed1984

Perforations of the temporomandibular joint meniscus: arthrographic, surgical, and clinical findings.

Arthrographic examination of the temporomandibular joint for perforations of the meniscus was found to be a reliable diagnostic test in a retrospective review of 45 surgical cases. Clinically palpable crepitus was also found to be an accurate indicator of the existence of perforations in patients who could open beyond 26 mm. The combination of palpable crepitus and a positive arthrogram was found to be complementary in diagnosing perforations and was confirmed by surgical observations.

Cartilage, Articular↗
PubMed1984

The validity of transcranial radiography in diagnosing TMJ anterior disk displacement.

Two transcranial radiographic methods for determining anterior disk displacement in the TMJ were evaluated in comparison with results obtained from arthrography. Both transcranial radiographic methods could only accurately predict the presence of an anteriorly displaced disk in a range of 26% to 56% of the time (for example, the methods gave false-negative results 44% to 74% of the time). The methods were more valuable in correctly identifying joints that were free of disease, achieving this identification anywhere from 64% to 96% of the time. Although noninvasive, these two transcranial radiographic techniques produced results that lacked validity and, therefore, remain of questionable value to the clinician who is diagnosing anterior disk displacement.

Cartilage, Articular↗
PubMed1982

Exchange of colicin receptor capacity between strains of Escherichia coli sensitive or resistant to colicin K-K235.

Phage and colicin-resistant mutants were derived from Escherichia coli K-12P678. Two classes of phage T6 and colicin K-resistant mutants (genotype tsx) were isolated. Tsx-2 mutants, which demonstrated mucoid growth and increased sensitivities to many antibiotics, became sensitive to colicin K when pretreated with ethylenediaminetetraacetate (EDTA), whereas Tsx-1 mutants did not. Reassociation of EDTA-released material partially restored resistance to colicin K for Tsx-2 mutants. When EDTA-released material from strain P678 was associated with either class of K-resistant mutant, an increase in colicin K sensitivity resulted. Observations suggest that colicin K can act on its target site once it penetrates the cell surface. In addition, results suggest that functional colicin K receptors can be transferred from sensitive to resistant strains, thus conferring colicin sensitivity.

Cell Membrane↗
PubMed1981

Heat Resistance and Population Stability of Lyophilized Bacillus subtilis Spores.

Bacillus subtilis 5230 spores were lyophilized in 0.067 M phosphate buffer and stored at 2 to 8 degrees C for 9 to 27 months. The lyophilized spores were reconstituted with buffer or 0.9% saline, and the heat resistance was determined in a thermoresistometer. Lyophilization had no effect on the heat resistance of the spores but did result in a slight decrease in population (</=0.3-logarithm reduction). The lyophilized spores maintained heat resistance and population levels over the test periods. The D-values ranged from 0.44 to 0.54 min at 121.1 degrees C, and the z-values ranged from 6.1 to 6.6 degrees C. Lyophilization was concluded to be an acceptable alternative for storage of bacterial spores that are to be used as biological indicators in sterilization processes.

Journal Article↗
PubMedDate not supplied

Industrial low-temperature gas plasma sterilization.

The search continues for alternative low-temperature sterilization technologies that do not exhibit adverse toxicological or environmental effects. Low-temperature plasma sterilization is one technology that is under investigation as an alternative to ethylene oxide and formaldehyde. This article examines the process and reports on the current status of the technology.

Gases↗
PubMedDate not supplied

Pulp response to the combined effects of cavity preparation and periodontal ligament injection.

Thirteen random-source dogs provided 54 experimental and 50 control teeth. Controls received either a periodontal ligament (PDL) injection only, or no injection, with deep cavities prepared and restored. Experimental teeth received both a PDL injection and the deep cavity preparation and were then restored with an IRM base and acid-etched composite. Teeth were surgically removed for observation periods of one and 18 weeks and prepared for histologic evaluation. Results indicated that, in this model system, there was little additive effect to the pulpal reaction due to the PDL injection. Controls that were prepared had essentially the same pulpal response as did the experimental teeth (PDL injection/preparation). In both experimental and control pulps, the effects were primarily related to the depth of the cavity preparation.

Anesthesia, Dental↗