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Biomedical subjects

G S Greene

Publications and source records attributed to G S Greene.

12 recordsLinked to original sources
PubMed1996

Case report: penicillin-resistant pneumococcal meningitis: navigating a therapeutic minefield.

Pneumococcal meningitis is a common infection in adults for which penicillin has long been the drug of choice. Optimal treatment has recently become controversial, however, owing to an alarming increase in the number of penicillin-resistant isolates. The authors report a representative case of meningitis caused by such an organism, and provide a discussion of the history, mechanisms of resistance, laboratory evaluation, and treatment of these infections. Guidelines for prevention are also reviewed, including a renewed call for utilization of the 23-valent pneumococcal vaccine.

Adult↗
PubMed1996

Ingestion of angel's trumpet: an increasingly common source of toxicity.

Angel's trumpet is a hallucinogenic plant commonly cultivated as an ornamental in the southeastern United States. Consumption of any part of the plant may result in severe anticholinergic toxicity. In past years, toxicity has largely resulted from accidental ingestion, but in 1994 there was a ten-fold increase in the number of reported ingestions throughout the state of Florida, largely by persons experimenting with the plant for its hallucinogenic effects. We report three such cases and review the literature on diagnosis, treatment, and sequelae of angel's trumpet intoxication.

Adolescent↗
PubMed1986

Infection in diabetic osteoarthropathy: use of indium-labeled leukocytes for diagnosis.

Indium-111 labeled leukocyte imaging was compared with three-phase skeletal scintigraphy as a means of determining whether osteomyelitis was complicating diabetic osteoarthropathy. Three-phase scintigraphy demonstrated increased activity in both infected and noninfected osteopathic bone, with a sensitivity of 75% and a specificity of 56% for osteomyelitis. Leukocyte imaging had the same sensitivity but was most helpful for excluding infection (specificity, 89%) when three-phase imaging could not. Abnormal leukocyte localization was seen at the primary site of infection in all cases within 4 hours after injection. Disadvantages of leukocyte imaging included long preparation time, low count rates resulting in poor spatial resolution, and absence of bone landmarks, which made it difficult to differentiate soft tissue from bone infection.

Adult↗
PubMed1984

Polyostotic fibrous dysplasia.

Fibrous dysplasia, a bone dysplasia of unknown pathogenesis, may be either monostotic or polyostotic. Not only is the femur involved in nearly all cases of the polyostotic form, but a distinct unilateral predilection is often noted. The following case illustrates the classic polyostotic changes.

Adult↗
PubMed1976

Adverse reaction to intravenous fluorescein: evidence for sex difference.

Males react adversely more frequently than females to intravenous fluorescein angiography, as shown in a study of 547 patients. Approximately 10% of all cases reacted: 12.8% of the male patients and 7.3% of the female patients had adverse responses. Nausea was most common; vomiting was infrequent, and urticaria rare (1.1%). Ten males as opposed to one female reacted markedly. More serious reactions did not occur during the 7 year testing period. No apparent cause for the increased frequency in the male cases was found.

Female↗