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Biomedical subjects

G S Karlin

Publications and source records attributed to G S Karlin.

7 recordsLinked to original sources
PubMed1990

Absence of persisting parenchymal damage after extracorporeal shock wave lithotripsy as judged by excretion of renal tubular enzymes.

Four renal tubular enzymes, N-acetyl-beta-glucosaminidase, beta-galactosidase, angiotensin-converting enzyme and gamma-glutamyltransferase, were measured in the urine before, and 24 hours and 1 week after extracorporeal shock wave lithotripsy in 20 consecutive patients. Extracorporeal shock wave lithotripsy was performed on the Sonolith 2000 device with the patient under intravenous narcotic sedation with fentanyl. Enzymatic activity per gram of urinary creatinine was consistently but not significantly higher before extracorporeal shock wave lithotripsy than in control subjects. All 4 enzymes were elevated 24 hours after extracorporeal shock wave lithotripsy, with the increases in beta-galactosidase and angiotensin-converting enzyme being statistically significant. However, by 7 days after the procedure the enzymes had decreased to pre-procedure concentrations or below. These data suggest that any renal tubular damage induced by extracorporeal shock wave lithotripsy is of limited magnitude and brief duration.

Acetylglucosaminidase↗
PubMed1990

Greenberg surgical support system for the endourologist.

As the field of endourology diversifies, the importance of ergonomics grows. The technology developed to assist the endourologist may accomplish the surgical goals effectively, but it often does not consider instrument control, planning of space, and the physical comfort of the operator. The Greenberg retractor creates a surgical environment that improves the urologist's efficiency and technical proficiency. Complex staghorn cases can be performed with reduced risk of inadvertent damage to renal tissue, no shifts of the nephroscope, and a more productive experience for the assistant.

Humans↗
PubMed1989

Approaches to the superior calix: renal displacement technique and review of options.

A new percutaneous approach to the superior calix has been implemented with reduced morbidity. To avoid intercostal or retrograde punctures or triangulation methods an Amplatz sheath passed through a central or lower pole calix can be pushed caudally while descent of the kidney is viewed fluoroscopically. An 18-gauge TLA needle passed through the initial skin puncture then is used to form a Y with the original tract. This method has been successful in 21 of 25 cases without complications. The only failures occurred in patients with immobile kidneys secondary to a previous operation.

Fluoroscopy↗
PubMed1988

Endopyelotomy versus open pyeloplasty: comparison in 88 patients.

We compared the results of the first 56 consecutive percutaneous corrections of ureteropelvic junction obstruction (endopyelotomy) at our institution with the most recent 32 consecutive cases of open pyeloplasty. The percutaneous procedure required less time (average 89.4 minutes versus 106.4 minutes for an open operation) and entailed less postoperative pain (60 per cent of the patients required an average of 4.7 unit doses of narcotics, whereas 88 per cent of the pyeloplasty patients required an average of 10.3 unit doses). The average hospital stay was less after endopyelotomy (average 6.2 versus 10.0 days) and return to normal activity occurred more quickly (average 19.8 versus 41.5 days). Endopyelotomy was successful in 87.5 per cent of the patients, with all failures being apparent within 6 weeks and they were easily correctable by traditional methods. Reported success rates of pyeloplasty ranged from 95 to 98 per cent.

Adolescent↗
PubMed1988

Treatment of ureteropelvic strictures with percutaneous pyelotomy: experience in 62 patients.

Percutaneous pyelotomy (endopyelotomy) is an endoscopic technique for the management of ureteropelvic junction obstruction. In a series of 62 consecutive patients, the success rate (measured by symptom-free status and improved uroradiographic findings) was 85%, including both primary and secondary obstructions. All failures were apparent within 3 months of the procedure and required open surgery. There were two major complications during the procedure. Our experience indicates that percutaneous pyelotomy is an effective alternative to traditional open pyeloplasty and has a similar success rate, lower morbidity, and a shorter recovery time.

Adolescent↗
PubMed1988

Endopyelotomy.

Endopyelotomy has developed from the advances of endourology and has become an accepted means to correct ureteropelvic junction obstruction. Endopyelotomy can be performed with less morbidity than pyeloplasty, with less operative and anesthetic time, less analgesic requirements, and a shorter recovery period. With success rates of 88.8 per cent for primary obstruction and 89 per cent for secondary obstruction, provided patients are selected appropriately, endopyelotomy has become a valuable procedure for the correction of ureteropelvic junction obstruction. The longest follow-up is 4 years, and therefore long-term success rates cannot be quoted. Time will reveal the ultimate place for endopyelotomy.

Catheters, Indwelling↗